Lori A Coburn, MD

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Publications

The following timeline graph is generated from all co-authored publications.

1. Dietary Arginine Regulates Severity of Experimental Colitis and Affects the Colonic Microbiome. Singh K, Gobert AP, Coburn LA, Barry DP, Allaman M, Asim M, Luis PB, Schneider C, Milne GL, Boone HH, Shilts MH, Washington MK, Das SR, Piazuelo MB, Wilson KT (2019) Front Cell Infect Microbiol : 66
   › Primary publication · 30972302 (PubMed) · PMC6443829 (PubMed Central)
2. Kaiso is required for MTG16-dependent effects on colitis-associated carcinoma. Short SP, Barrett CW, Stengel KR, Revetta FL, Choksi YA, Coburn LA, Lintel MK, McDonough EM, Washington MK, Wilson KT, Prokhortchouk E, Chen X, Hiebert SW, Reynolds AB, Williams CS (2019) Oncogene 38(25): 5091-5106
   › Primary publication · 30858547 (PubMed) · PMC6586520 (PubMed Central)
3. Serum Polyunsaturated Fatty Acids Correlate with Serum Cytokines and Clinical Disease Activity in Crohn's Disease. Scoville EA, Allaman MM, Adams DW, Motley AK, Peyton SC, Ferguson SL, Horst SN, Williams CS, Beaulieu DB, Schwartz DA, Wilson KT, Coburn LA (2019) Sci Rep 9(1): 2882
   › Primary publication · 30814550 (PubMed) · PMC6393448 (PubMed Central)
4. Loss of solute carrier family 7 member 2 exacerbates inflammation-associated colon tumorigenesis. Coburn LA, Singh K, Asim M, Barry DP, Allaman MM, Al-Greene NT, Hardbower DM, Polosukhina D, Williams CS, Delgado AG, Piazuelo MB, Washington MK, Gobert AP, Wilson KT (2019) Oncogene 38(7): 1067-1079
   › Primary publication · 30202097 (PubMed) · PMC6377304 (PubMed Central)
5. Distinct Immunomodulatory Effects of Spermine Oxidase in Colitis Induced by Epithelial Injury or Infection. Gobert AP, Al-Greene NT, Singh K, Coburn LA, Sierra JC, Verriere TG, Luis PB, Schneider C, Asim M, Allaman MM, Barry DP, Cleveland JL, Destefano Shields CE, Casero RA, Washington MK, Piazuelo MB, Wilson KT (2018) Front Immunol : 1242
   › Primary publication · 29922289 (PubMed) · PMC5996034 (PubMed Central)
6. BVES is required for maintenance of colonic epithelial integrity in experimental colitis by modifying intestinal permeability. Choksi YA, Reddy VK, Singh K, Barrett CW, Short SP, Parang B, Keating CE, Thompson JJ, Verriere TG, Brown RE, Piazuelo MB, Bader DM, Washington MK, Mittal MK, Brand T, Gobert AP, Coburn LA, Wilson KT, Williams CS (2018) Mucosal Immunol 11(5): 1363-1374
   › Primary publication · 29907869 (PubMed) · PMC6162166 (PubMed Central)
7. Ornithine Decarboxylase in Macrophages Exacerbates Colitis and Promotes Colitis-Associated Colon Carcinogenesis by Impairing M1 Immune Responses. Singh K, Coburn LA, Asim M, Barry DP, Allaman MM, Shi C, Washington MK, Luis PB, Schneider C, Delgado AG, Piazuelo MB, Cleveland JL, Gobert AP, Wilson KT (2018) Cancer Res 78(15): 4303-4315
   › Primary publication · 29853605 (PubMed) · PMC6072585 (PubMed Central)
8. Alterations in Lipid, Amino Acid, and Energy Metabolism Distinguish Crohn's Disease from Ulcerative Colitis and Control Subjects by Serum Metabolomic Profiling. Scoville EA, Allaman MM, Brown CT, Motley AK, Horst SN, Williams CS, Koyama T, Zhao Z, Adams DW, Beaulieu DB, Schwartz DA, Wilson KT, Coburn LA (2018) Metabolomics 14(1): 17
   › Primary publication · 29681789 (PubMed) · PMC5907923 (PubMed Central)
9. MTG16 is a tumor suppressor in colitis-associated carcinoma. McDonough EM, Barrett CW, Parang B, Mittal MK, Smith JJ, Bradley AM, Choksi YA, Coburn LA, Short SP, Thompson JJ, Zhang B, Poindexter SV, Fischer MA, Chen X, Li J, Revetta FL, Naik R, Washington MK, Rosen MJ, Hiebert SW, Wilson KT, Williams CS (2017) JCI Insight 2(16)
   › Primary publication · 28814670 (PubMed) · PMC5621889 (PubMed Central)
10. EGFR-mediated macrophage activation promotes colitis-associated tumorigenesis. Hardbower DM, Coburn LA, Asim M, Singh K, Sierra JC, Barry DP, Gobert AP, Piazuelo MB, Washington MK, Wilson KT (2017) Oncogene 36(27): 3807-3819
    › Primary publication · 28263971 (PubMed) · PMC5501754 (PubMed Central)
11. The L-Arginine Transporter Solute Carrier Family 7 Member 2 Mediates the Immunopathogenesis of Attaching and Effacing Bacteria. Singh K, Al-Greene NT, Verriere TG, Coburn LA, Asim M, Barry DP, Allaman MM, Hardbower DM, Delgado AG, Piazuelo MB, Vallance BA, Gobert AP, Wilson KT (2016) PLoS Pathog 12(10): e1005984
    › Primary publication · 27783672 (PubMed) · PMC5081186 (PubMed Central)
12. The Role of the Microbiome in Gastrointestinal Cancer. Wroblewski LE, Peek RM, Coburn LA (2016) Gastroenterol Clin North Am 45(3): 543-56
    › Primary publication · 27546848 (PubMed) · PMC4994977 (PubMed Central)
13. Serum Fatty Acids Are Correlated with Inflammatory Cytokines in Ulcerative Colitis. Wiese DM, Horst SN, Brown CT, Allaman MM, Hodges ME, Slaughter JC, Druce JP, Beaulieu DB, Schwartz DA, Wilson KT, Coburn LA (2016) PLoS One 11(5): e0156387
    › Primary publication · 27227540 (PubMed) · PMC4882051 (PubMed Central)
14. L-Arginine Availability and Metabolism Is Altered in Ulcerative Colitis. Coburn LA, Horst SN, Allaman MM, Brown CT, Williams CS, Hodges ME, Druce JP, Beaulieu DB, Schwartz DA, Wilson KT (2016) Inflamm Bowel Dis 22(8): 1847-58
    › Primary publication · 27104830 (PubMed) · PMC4956554 (PubMed Central)
15. IL-33 Signaling Protects from Murine Oxazolone Colitis by Supporting Intestinal Epithelial Function. Waddell A, Vallance JE, Moore PD, Hummel AT, Wu D, Shanmukhappa SK, Fei L, Washington MK, Minar P, Coburn LA, Nakae S, Wilson KT, Denson LA, Hogan SP, Rosen MJ (2015) Inflamm Bowel Dis 21(12): 2737-46
    › Primary publication · 26313694 (PubMed) · PMC4654638 (PubMed Central)
16. High-throughput multi-analyte Luminex profiling implicates eotaxin-1 in ulcerative colitis. Coburn LA, Horst SN, Chaturvedi R, Brown CT, Allaman MM, Scull BP, Singh K, Piazuelo MB, Chitnavis MV, Hodges ME, Rosen MJ, Williams CS, Slaughter JC, Beaulieu DB, Schwartz DA, Wilson KT (2013) PLoS One 8(12): e82300
    › Primary publication · 24367513 (PubMed) · PMC3867379 (PubMed Central)
17. Deletion of cationic amino acid transporter 2 exacerbates dextran sulfate sodium colitis and leads to an IL-17-predominant T cell response. Singh K, Coburn LA, Barry DP, Asim M, Scull BP, Allaman MM, Lewis ND, Washington MK, Rosen MJ, Williams CS, Chaturvedi R, Wilson KT (2013) Am J Physiol Gastrointest Liver Physiol 305(3): G225-40
    › Primary publication · 23703655 (PubMed) · PMC3742860 (PubMed Central)
18. STAT6 deficiency ameliorates severity of oxazolone colitis by decreasing expression of claudin-2 and Th2-inducing cytokines. Rosen MJ, Chaturvedi R, Washington MK, Kuhnhein LA, Moore PD, Coggeshall SS, McDonough EM, Weitkamp JH, Singh AB, Coburn LA, Williams CS, Yan F, Van Kaer L, Peebles RS, Wilson KT (2013) J Immunol 190(4): 1849-58
    › Primary publication · 23303670 (PubMed) · PMC3563924 (PubMed Central)
19. Tumor suppressor function of the plasma glutathione peroxidase gpx3 in colitis-associated carcinoma. Barrett CW, Ning W, Chen X, Smith JJ, Washington MK, Hill KE, Coburn LA, Peek RM, Chaturvedi R, Wilson KT, Burk RF, Williams CS (2013) Cancer Res 73(3): 1245-55
    › Primary publication · 23221387 (PubMed) · PMC3563732 (PubMed Central)
20. MTG16 contributes to colonic epithelial integrity in experimental colitis. Williams CS, Bradley AM, Chaturvedi R, Singh K, Piazuelo MB, Chen X, McDonough EM, Schwartz DA, Brown CT, Allaman MM, Coburn LA, Horst SN, Beaulieu DB, Choksi YA, Washington MK, Williams AD, Fisher MA, Zinkel SS, Peek RM, Wilson KT, Hiebert SW (2013) Gut 62(10): 1446-55
    › Primary publication · 22833394 (PubMed) · PMC3663894 (PubMed Central)
21. L-arginine supplementation improves responses to injury and inflammation in dextran sulfate sodium colitis. Coburn LA, Gong X, Singh K, Asim M, Scull BP, Allaman MM, Williams CS, Rosen MJ, Washington MK, Barry DP, Piazuelo MB, Casero RA, Chaturvedi R, Zhao Z, Wilson KT (2012) PLoS One 7(3): e33546
    › Primary publication · 22428068 (PubMed) · PMC3299802 (PubMed Central)
22. L-arginine uptake by cationic amino acid transporter 2 is essential for colonic epithelial cell restitution. Singh K, Coburn LA, Barry DP, Boucher JL, Chaturvedi R, Wilson KT (2012) Am J Physiol Gastrointest Liver Physiol 302(9): G1061-73
    › Primary publication · 22361732 (PubMed) · PMC3362080 (PubMed Central)
23. Cationic amino acid transporter 2 enhances innate immunity during Helicobacter pylori infection. Barry DP, Asim M, Scull BP, Piazuelo MB, de Sablet T, Lewis ND, Coburn LA, Singh K, Ellies LG, Gobert AP, Chaturvedi R, Wilson KT (2011) PLoS One 6(12): e29046
    › Primary publication · 22194986 (PubMed) · PMC3237590 (PubMed Central)
24. Arginine and polyamines in Helicobacter pylori-induced immune dysregulation and gastric carcinogenesis. Chaturvedi R, de Sablet T, Coburn LA, Gobert AP, Wilson KT (2012) Amino Acids 42(2-3): 627-40
    › Primary publication · 21874531 (PubMed) · PMC3258477 (PubMed Central)
25. The apolipoprotein E-mimetic peptide COG112 inhibits NF-kappaB signaling, proinflammatory cytokine expression, and disease activity in murine models of colitis. Singh K, Chaturvedi R, Barry DP, Coburn LA, Asim M, Lewis ND, Piazuelo MB, Washington MK, Vitek MP, Wilson KT (2011) J Biol Chem 286(5): 3839-50
    › Primary publication · 21115487 (PubMed) · PMC3030385 (PubMed Central)
26. Increased expression and cellular localization of spermine oxidase in ulcerative colitis and relationship to disease activity. Hong SK, Chaturvedi R, Piazuelo MB, Coburn LA, Williams CS, Delgado AG, Casero RA, Schwartz DA, Wilson KT (2010) Inflamm Bowel Dis 16(9): 1557-66
    › Primary publication · 20127992 (PubMed) · PMC2894261 (PubMed Central)
27. Increased serum levels of L-arginine in ulcerative colitis and correlation with disease severity. Hong SK, Maltz BE, Coburn LA, Slaughter JC, Chaturvedi R, Schwartz DA, Wilson KT (2010) Inflamm Bowel Dis 16(1): 105-11
    › Primary publication · 19637336 (PubMed) · PMC2795785 (PubMed Central)
28. The successful use of adalimumab to treat active Crohn's disease of an ileoanal pouch during pregnancy. Coburn LA, Wise PE, Schwartz DA (2006) Dig Dis Sci 51(11): 2045-7
    › Primary publication · 17009112 (PubMed)

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