Disability income, cocaine use, and repeated hospitalization among schizophrenic cocaine abusers--a government-sponsored revolving door? Shaner A, Eckman TA, Roberts LJ, Wilkins JN, Tucker DE, Tsuang JW, Mintz J (1995) N Engl J Med 333: 777-83 Expression cloning of a cocaine- and antidepressant-sensitive human noradrenaline transporter. Pacholczyk T, Blakely RD, Amara SG (1991) Nature 350: 350-4 Prenatal exposure to drugs: effects on brain development and implications for policy and education. Thompson BL, Levitt P, Stanwood GD (2009) Nat Rev Neurosci 10: 303-12 Phosphorylation and sequestration of serotonin transporters differentially modulated by psychostimulants. Ramamoorthy S, Blakely RD (1999) Science 285: 763-6 GLP-1 analog attenuates cocaine reward. Graham DL, Erreger K, Galli A, Stanwood GD (2013) Mol Psychiatry 18: 961-2 Functional magnetic resonance imaging of cocaine craving. Wexler BE, Gottschalk CH, Fulbright RK, Prohovnik I, Lacadie CM, Rounsaville BJ, Gore JC (2001) Am J Psychiatry 158: 86-95 Transgenic elimination of high-affinity antidepressant and cocaine sensitivity in the presynaptic serotonin transporter. Thompson BJ, Jessen T, Henry LK, Field JR, Gamble KL, Gresch PJ, Carneiro AM, Horton RE, Chisnell PJ, Belova Y, McMahon DG, Daws LC, Blakely RD (2011) Proc Natl Acad Sci U S A 108: 3785-90 Amphetamine-induced loss of human dopamine transporter activity: an internalization-dependent and cocaine-sensitive mechanism. Saunders C, Ferrer JV, Shi L, Chen J, Merrill G, Lamb ME, Leeb-Lundberg LM, Carvelli L, Javitch JA, Galli A (2000) Proc Natl Acad Sci U S A 97: 6850-5 Antidepressant- and cocaine-sensitive human serotonin transporter: molecular cloning, expression, and chromosomal localization. Ramamoorthy S, Bauman AL, Moore KR, Han H, Yang-Feng T, Chang AS, Ganapathy V, Blakely RD (1993) Proc Natl Acad Sci U S A 90: 2542-6 Cloning, expression, and localization of a chloride-facilitated, cocaine-sensitive serotonin transporter from Drosophila melanogaster. Demchyshyn LL, Pristupa ZB, Sugamori KS, Barker EL, Blakely RD, Wolfgang WJ, Forte MA, Niznik HB (1994) Proc Natl Acad Sci U S A 91: 5158-62 A shift in the role of glutamatergic signaling in the nucleus accumbens core with the development of an addicted phenotype. Doyle SE, Ramôa C, Garber G, Newman J, Toor Z, Lynch WJ (2014) Biol Psychiatry 76: 810-5 β-Adrenergic receptors enhance excitatory transmission in the bed nucleus of the stria terminalis through a corticotrophin-releasing factor receptor-dependent and cocaine-regulated mechanism. Nobis WP, Kash TL, Silberman Y, Winder DG (2011) Biol Psychiatry 69: 1083-90 Binge cocaine administration in adolescent rats affects amygdalar gene expression patterns and alters anxiety-related behavior in adulthood. Sillivan SE, Black YD, Naydenov AV, Vassoler FR, Hanlin RP, Konradi C (2011) Biol Psychiatry 70: 583-92 Drug-induced activation of dopamine D(1) receptor signaling and inhibition of class I/II histone deacetylase induce chromatin remodeling in reward circuitry and modulate cocaine-related behaviors. Schroeder FA, Penta KL, Matevossian A, Jones SR, Konradi C, Tapper AR, Akbarian S (2008) Neuropsychopharmacology 33: 2981-92 Yohimbine depresses excitatory transmission in BNST and impairs extinction of cocaine place preference through orexin-dependent, norepinephrine-independent processes. Conrad KL, Davis AR, Silberman Y, Sheffler DJ, Shields AD, Saleh SA, Sen N, Matthies HJ, Javitch JA, Lindsley CW, Winder DG (2012) Neuropsychopharmacology 37: 2253-66 Cocaine self-administration reduces excitatory responses in the mouse nucleus accumbens shell. Schramm-Sapyta NL, Olsen CM, Winder DG (2006) Neuropsychopharmacology 31: 1444-51 The mGluR2 positive allosteric modulator BINA decreases cocaine self-administration and cue-induced cocaine-seeking and counteracts cocaine-induced enhancement of brain reward function in rats. Jin X, Semenova S, Yang L, Ardecky R, Sheffler DJ, Dahl R, Conn PJ, Cosford ND, Markou A (2010) Neuropsychopharmacology 35: 2021-36 Serotonin transporter inhibition and 5-HT receptor activation drive loss of cocaine-induced locomotor activation in DAT Val559 mice. Stewart A, Davis GL, Gresch PJ, Katamish RM, Peart R, Rabil MJ, Gowrishankar R, Carroll FI, Hahn MK, Blakely RD (2019) Neuropsychopharmacology 44: 994-1006 Genetic loss of GluN2B in D1-expressing cell types enhances long-term cocaine reward and potentiation of thalamo-accumbens synapses. Joffe ME, Turner BD, Delpire E, Grueter BA (2018) Neuropsychopharmacology 43: 2383-2389 Partial mGlu₅ Negative Allosteric Modulators Attenuate Cocaine-Mediated Behaviors and Lack Psychotomimetic-Like Effects. Gould RW, Amato RJ, Bubser M, Joffe ME, Nedelcovych MT, Thompson AD, Nickols HH, Yuh JP, Zhan X, Felts AS, Rodriguez AL, Morrison RD, Byers FW, Rook JM, Daniels JS, Niswender CM, Conn PJ, Emmitte KA, Lindsley CW, Jones CK (2016) Neuropsychopharmacology 41: 1166-78 Functional status of the serotonin 5-HT2C receptor (5-HT2CR) drives interlocked phenotypes that precipitate relapse-like behaviors in cocaine dependence. Anastasio NC, Stutz SJ, Fox RG, Sears RM, Emeson RB, DiLeone RJ, O'Neil RT, Fink LH, Li D, Green TA, Moeller FG, Cunningham KA (2014) Neuropsychopharmacology 39: 370-82 Locus coeruleus kappa-opioid receptors modulate reinstatement of cocaine place preference through a noradrenergic mechanism. Al-Hasani R, McCall JG, Foshage AM, Bruchas MR (2013) Neuropsychopharmacology 38: 2484-97 Alpha1-adrenergic receptor-induced heterosynaptic long-term depression in the bed nucleus of the stria terminalis is disrupted in mouse models of affective disorders. McElligott ZA, Winder DG (2008) Neuropsychopharmacology 33: 2313-23 Phosphorylation of DARPP-32 at Threonine-34 is required for cocaine action. Zachariou V, Sgambato-Faure V, Sasaki T, Svenningsson P, Berton O, Fienberg AA, Nairn AC, Greengard P, Nestler EJ (2006) Neuropsychopharmacology 31: 555-62 Amphetamine regulates gene expression in rat striatum via transcription factor CREB. Konradi C, Cole RL, Heckers S, Hyman SE (1994) J Neurosci 14: 5623-34 Transmembrane domain I contributes to the permeation pathway for serotonin and ions in the serotonin transporter. Barker EL, Moore KR, Rakhshan F, Blakely RD (1999) J Neurosci 19: 4705-17 Altered responsiveness to cocaine and increased immobility in the forced swim test associated with elevated cAMP response element-binding protein expression in nucleus accumbens. Pliakas AM, Carlson RR, Neve RL, Konradi C, Nestler EJ, Carlezon WA (2001) J Neurosci 21: 7397-403 cAMP response element-binding protein is required for dopamine-dependent gene expression in the intact but not the dopamine-denervated striatum. Andersson M, Konradi C, Cenci MA (2001) J Neurosci 21: 9930-43 AKAP signaling in reinstated cocaine seeking revealed by iTRAQ proteomic analysis. Reissner KJ, Uys JD, Schwacke JH, Comte-Walters S, Rutherford-Bethard JL, Dunn TE, Blumer JB, Schey KL, Kalivas PW (2011) J Neurosci 31: 5648-58 Extracellular-signal regulated kinase 1-dependent metabotropic glutamate receptor 5-induced long-term depression in the bed nucleus of the stria terminalis is disrupted by cocaine administration. Grueter BA, Gosnell HB, Olsen CM, Schramm-Sapyta NL, Nekrasova T, Landreth GE, Winder DG (2006) J Neurosci 26: 3210-9 Dopamine enhances fast excitatory synaptic transmission in the extended amygdala by a CRF-R1-dependent process. Kash TL, Nobis WP, Matthews RT, Winder DG (2008) J Neurosci 28: 13856-65 Cocaine and antidepressant-sensitive biogenic amine transporters exist in regulated complexes with protein phosphatase 2A. Bauman AL, Apparsundaram S, Ramamoorthy S, Wadzinski BE, Vaughan RA, Blakely RD (2000) J Neurosci 20: 7571-8 In vivo metabotropic glutamate receptor 5 (mGluR5) antagonism prevents cocaine-induced disruption of postsynaptically maintained mGluR5-dependent long-term depression. Grueter BA, McElligott ZA, Robison AJ, Mathews GC, Winder DG (2008) J Neurosci 28: 9261-70 Altered sensitivity to rewarding and aversive drugs in mice with inducible disruption of cAMP response element-binding protein function within the nucleus accumbens. Dinieri JA, Nemeth CL, Parsegian A, Carle T, Gurevich VV, Gurevich E, Neve RL, Nestler EJ, Carlezon WA (2009) J Neurosci 29: 1855-9 Altered attention and prefrontal cortex gene expression in rats after binge-like exposure to cocaine during adolescence. Black YD, Maclaren FR, Naydenov AV, Carlezon WA, Baxter MG, Konradi C (2006) J Neurosci 26: 9656-65 Psychostimulant-induced Fos protein expression in the thalamic paraventricular nucleus. Deutch AY, Bubser M, Young CD (1998) J Neurosci 18: 10680-7 Prenatal exposure to cocaine produces unique developmental and long-term adaptive changes in dopamine D1 receptor activity and subcellular distribution. Stanwood GD, Levitt P (2007) J Neurosci 27: 152-7
Hints: (1) double-click or double-tap to navigate to a node. (2) Grab a node and move it to arrange the graph.