Keyword Connections

•  Antonis Hatzopoulos
•  Bryan Venters
•  Chee Lim
•  Chris Wright
•  David Gailani
•  Douglas Mortlock

•  Gregor Neuert
•  H. Ruley
•  Manuel Ascano
•  Maria Hadjifrangiskou
•  Robert Beauchamp
•  Robert Matusik

•  Scott Baldwin
•  Scott Hiebert
•  Simon Hayward
•  Stephen Hann
•  Thomas Aune

Resources

• No matching connections

Communities

• Baldwin Lab
• Hatzopoulos Lab
• Hiebert Lab
• Matusik Lab
• Mortlock Lab
• Wright Lab

Publications

• RAS mutations in cutaneous squamous-cell carcinomas in patients treated with BRAF inhibitors.
  Su F, Viros A, Milagre C, Trunzer K, Bollag G, Spleiss O, Reis-Filho JS, Kong X, Koya RC, Flaherty KT, Chapman PB, Kim MJ, Hayward R, Martin M, Yang H, Wang Q, Hilton H, Hang JS, Noe J, Lambros M, Geyer F, Dhomen N, Niculescu-Duvaz I, Zambon A, Niculescu-Duvaz D, Preece N, Robert L, Otte NJ, Mok S, Kee D, Ma Y, Zhang C, Habets G, Burton EA, Wong B, Nguyen H, Kockx M, Andries L, Lestini B, Nolop KB, Lee RJ, Joe AK, Troy JL, Gonzalez R, Hutson TE, Puzanov I, Chmielowski B, Springer CJ, McArthur GA, Sosman JA, Lo RS, Ribas A, Marais R
  (2012) N Engl J Med 366: 207-15
• K-ras oncogene activation as a prognostic marker in adenocarcinoma of the lung.
  Slebos RJ, Kibbelaar RE, Dalesio O, Kooistra A, Stam J, Meijer CJ, Wagenaar SS, Vanderschueren RG, van Zandwijk N, Mooi WJ
  (1990) N Engl J Med 323: 561-5
• Proteomic patterns of tumour subsets in non-small-cell lung cancer.
  Yanagisawa K, Shyr Y, Xu BJ, Massion PP, Larsen PH, White BC, Roberts JR, Edgerton M, Gonzalez A, Nadaf S, Moore JH, Caprioli RM, Carbone DP
  (2003) Lancet 362: 433-9
• Glucose transporter gene and non-insulin-dependent diabetes.
  Cox NJ, Xiang KS, Bell GI, Karam JH
  (1988) Lancet 2: 793-4
• Nucleosome organization in the Drosophila genome.
  Mavrich TN, Jiang C, Ioshikhes IP, Li X, Venters BJ, Zanton SJ, Tomsho LP, Qi J, Glaser RL, Schuster SC, Gilmour DS, Albert I, Pugh BF
  (2008) Nature 453: 358-62
• Adenovirus early region 1A enables viral and cellular transforming genes to transform primary cells in culture.
  Ruley HE
  (1983) Nature 304: 602-6
• Comprehensive molecular portraits of human breast tumours.
  Cancer Genome Atlas Network
  (2012) Nature 490: 61-70
• Comprehensive molecular characterization of gastric adenocarcinoma.
  Cancer Genome Atlas Research Network
  (2014) Nature 513: 202-9
• Genetic effects on gene expression across human tissues.
  GTEx Consortium, Laboratory, Data Analysis &Coordinating Center (LDACC)—Analysis Working Group, Statistical Methods groups—Analysis Working Group, Enhancing GTEx (eGTEx) groups, NIH Common Fund, NIH/NCI, NIH/NHGRI, NIH/NIMH, NIH/NIDA, Biospecimen Collection Source Site—NDRI, Biospecimen Collection Source Site—RPCI, Biospecimen Core Resource—VARI, Brain Bank Repository—University of Miami Brain Endowment Bank, Leidos Biomedical—Project Management, ELSI Study, Genome Browser Data Integration &Visualization—EBI, Genome Browser Data Integration &Visualization—UCSC Genomics Institute, University of California Santa Cruz, Lead analysts:, Laboratory, Data Analysis &Coordinating Center (LDACC):, NIH program management:, Biospecimen collection:, Pathology:, eQTL manuscript working group:, Battle A, Brown CD, Engelhardt BE, Montgomery SB
  (2017) Nature 550: 204-213
• Deterministic direct reprogramming of somatic cells to pluripotency.
  Rais Y, Zviran A, Geula S, Gafni O, Chomsky E, Viukov S, Mansour AA, Caspi I, Krupalnik V, Zerbib M, Maza I, Mor N, Baran D, Weinberger L, Jaitin DA, Lara-Astiaso D, Blecher-Gonen R, Shipony Z, Mukamel Z, Hagai T, Gilad S, Amann-Zalcenstein D, Tanay A, Amit I, Novershtern N, Hanna JH
  (2013) Nature 502: 65-70
• Active medulloblastoma enhancers reveal subgroup-specific cellular origins.
  Lin CY, Erkek S, Tong Y, Yin L, Federation AJ, Zapatka M, Haldipur P, Kawauchi D, Risch T, Warnatz HJ, Worst BC, Ju B, Orr BA, Zeid R, Polaski DR, Segura-Wang M, Waszak SM, Jones DT, Kool M, Hovestadt V, Buchhalter I, Sieber L, Johann P, Chavez L, Gröschel S, Ryzhova M, Korshunov A, Chen W, Chizhikov VV, Millen KJ, Amstislavskiy V, Lehrach H, Yaspo ML, Eils R, Lichter P, Korbel JO, Pfister SM, Bradner JE, Northcott PA
  (2016) Nature 530: 57-62
• The inhibitory cytokine IL-35 contributes to regulatory T-cell function.
  Collison LW, Workman CJ, Kuo TT, Boyd K, Wang Y, Vignali KM, Cross R, Sehy D, Blumberg RS, Vignali DA
  (2007) Nature 450: 566-9
• Shh and Gli3 are dispensable for limb skeleton formation but regulate digit number and identity.
  Litingtung Y, Dahn RD, Li Y, Fallon JF, Chiang C
  (2002) Nature 418: 979-83
• Mutations in the hepatocyte nuclear factor-4alpha gene in maturity-onset diabetes of the young (MODY1)
  Yamagata K, Furuta H, Oda N, Kaisaki PJ, Menzel S, Cox NJ, Fajans SS, Signorini S, Stoffel M, Bell GI
  (1996) Nature 384: 458-60
• Non-optimal codon usage is a mechanism to achieve circadian clock conditionality.
  Xu Y, Ma P, Shah P, Rokas A, Liu Y, Johnson CH
  (2013) Nature 495: 116-20
• Comprehensive genomic characterization of head and neck squamous cell carcinomas.
  Cancer Genome Atlas Network
  (2015) Nature 517: 576-82
• Translational control in homoeobox mRNAs?
  Bürglin TR, Wright CV, De Robertis EM
  (1987) Nature 330: 701-2
• Alternative production of calcitonin and CGRP mRNA is regulated at the calcitonin-specific splice acceptor.
  Emeson RB, Hedjran F, Yeakley JM, Guise JW, Rosenfeld MG
  (1989) Nature 341: 76-80
• Pseudogene-derived small interfering RNAs regulate gene expression in mouse oocytes.
  Tam OH, Aravin AA, Stein P, Girard A, Murchison EP, Cheloufi S, Hodges E, Anger M, Sachidanandam R, Schultz RM, Hannon GJ
  (2008) Nature 453: 534-8
• TBP-associated factors are not generally required for transcriptional activation in yeast.
  Moqtaderi Z, Bai Y, Poon D, Weil PA, Struhl K
  (1996) Nature 383: 188-91
• Inhibition of nuclear hormone receptor activity by calreticulin.
  Dedhar S, Rennie PS, Shago M, Hagesteijn CY, Yang H, Filmus J, Hawley RG, Bruchovsky N, Cheng H, Matusik RJ
  (1994) Nature 367: 480-3
• A diurnal serum lipid integrates hepatic lipogenesis and peripheral fatty acid use.
  Liu S, Brown JD, Stanya KJ, Homan E, Leidl M, Inouye K, Bhargava P, Gangl MR, Dai L, Hatano B, Hotamisligil GS, Saghatelian A, Plutzky J, Lee CH
  (2013) Nature 502: 550-4
• Effects of oncogenic mutations in Smoothened and Patched can be reversed by cyclopamine.
  Taipale J, Chen JK, Cooper MK, Wang B, Mann RK, Milenkovic L, Scott MP, Beachy PA
  (2000) Nature 406: 1005-9
• Hypothalamic CART is a new anorectic peptide regulated by leptin.
  Kristensen P, Judge ME, Thim L, Ribel U, Christjansen KN, Wulff BS, Clausen JT, Jensen PB, Madsen OD, Vrang N, Larsen PJ, Hastrup S
  (1998) Nature 393: 72-6
• p19ARF directly and differentially controls the functions of c-Myc independently of p53.
  Qi Y, Gregory MA, Li Z, Brousal JP, West K, Hann SR
  (2004) Nature 431: 712-7
• Conserved left-right asymmetry of nodal expression and alterations in murine situs inversus.
  Lowe LA, Supp DM, Sampath K, Yokoyama T, Wright CV, Potter SS, Overbeek P, Kuehn MR
  (1996) Nature 381: 158-61
• Production and auto-induction of transforming growth factor-alpha in human keratinocytes.
  Coffey RJ, Derynck R, Wilcox JN, Bringman TS, Goustin AS, Moses HL, Pittelkow MR
  (1987) Nature 328: 817-20
• Regulation of alternative splicing by RNA editing.
  Rueter SM, Dawson TR, Emeson RB
  (1999) Nature 399: 75-80
• Human genetics: an expression of interest.
  Cox NJ
  (2004) Nature 430: 733-4
• Inhibition of NF-kappaB activity results in disruption of the apical ectodermal ridge and aberrant limb morphogenesis.
  Bushdid PB, Brantley DM, Yull FE, Blaeuer GL, Hoffman LH, Niswander L, Kerr LD
  (1998) Nature 392: 615-8
• Melanomas acquire resistance to B-RAF(V600E) inhibition by RTK or N-RAS upregulation.
  Nazarian R, Shi H, Wang Q, Kong X, Koya RC, Lee H, Chen Z, Lee MK, Attar N, Sazegar H, Chodon T, Nelson SF, McArthur G, Sosman JA, Ribas A, Lo RS
  (2010) Nature 468: 973-7
• Discovery of functional elements in 12 Drosophila genomes using evolutionary signatures.
  Stark A, Lin MF, Kheradpour P, Pedersen JS, Parts L, Carlson JW, Crosby MA, Rasmussen MD, Roy S, Deoras AN, Ruby JG, Brennecke J, Harvard FlyBase curators, Berkeley Drosophila Genome Project, Hodges E, Hinrichs AS, Caspi A, Paten B, Park SW, Han MV, Maeder ML, Polansky BJ, Robson BE, Aerts S, van Helden J, Hassan B, Gilbert DG, Eastman DA, Rice M, Weir M, Hahn MW, Park Y, Dewey CN, Pachter L, Kent WJ, Haussler D, Lai EC, Bartel DP, Hannon GJ, Kaufman TC, Eisen MB, Clark AG, Smith D, Celniker SE, Gelbart WM, Kellis M
  (2007) Nature 450: 219-32
• Comprehensive molecular profiling of lung adenocarcinoma.
  Cancer Genome Atlas Research Network
  (2014) Nature 511: 543-50
• Somatic mutations affect key pathways in lung adenocarcinoma.
  Ding L, Getz G, Wheeler DA, Mardis ER, McLellan MD, Cibulskis K, Sougnez C, Greulich H, Muzny DM, Morgan MB, Fulton L, Fulton RS, Zhang Q, Wendl MC, Lawrence MS, Larson DE, Chen K, Dooling DJ, Sabo A, Hawes AC, Shen H, Jhangiani SN, Lewis LR, Hall O, Zhu Y, Mathew T, Ren Y, Yao J, Scherer SE, Clerc K, Metcalf GA, Ng B, Milosavljevic A, Gonzalez-Garay ML, Osborne JR, Meyer R, Shi X, Tang Y, Koboldt DC, Lin L, Abbott R, Miner TL, Pohl C, Fewell G, Haipek C, Schmidt H, Dunford-Shore BH, Kraja A, Crosby SD, Sawyer CS, Vickery T, Sander S, Robinson J, Winckler W, Baldwin J, Chirieac LR, Dutt A, Fennell T, Hanna M, Johnson BE, Onofrio RC, Thomas RK, Tonon G, Weir BA, Zhao X, Ziaugra L, Zody MC, Giordano T, Orringer MB, Roth JA, Spitz MR, Wistuba II, Ozenberger B, Good PJ, Chang AC, Beer DG, Watson MA, Ladanyi M, Broderick S, Yoshizawa A, Travis WD, Pao W, Province MA, Weinstock GM, Varmus HE, Gabriel SB, Lander ES, Gibbs RA, Meyerson M, Wilson RK
  (2008) Nature 455: 1069-75
• Gene expression: The autism disconnect.
  Korade Z, Mirnics K
  (2011) Nature 474: 294-5
• The molecular basis of hypodactyly (Hd): a deletion in Hoxa 13 leads to arrest of digital arch formation.
  Mortlock DP, Post LC, Innis JW
  (1996) Nat Genet 13: 284-9
• Secretory COPII coat component Sec23a is essential for craniofacial chondrocyte maturation.
  Lang MR, Lapierre LA, Frotscher M, Goldenring JR, Knapik EW
  (2006) Nat Genet 38: 1198-203
• The role of the transcriptional regulator Ptf1a in converting intestinal to pancreatic progenitors.
  Kawaguchi Y, Cooper B, Gannon M, Ray M, MacDonald RJ, Wright CV
  (2002) Nat Genet 32: 128-34
• Spatiotemporal regulation of endothelin receptor-B by SOX10 in neural crest-derived enteric neuron precursors.
  Zhu L, Lee HO, Jordan CS, Cantrell VA, Southard-Smith EM, Shin MK
  (2004) Nat Genet 36: 732-7
• Increased methylation variation in epigenetic domains across cancer types.
  Hansen KD, Timp W, Bravo HC, Sabunciyan S, Langmead B, McDonald OG, Wen B, Wu H, Liu Y, Diep D, Briem E, Zhang K, Irizarry RA, Feinberg AP
  (2011) Nat Genet 43: 768-75