NK cells promote islet allograft tolerance via a perforin-dependent mechanism. Beilke JN, Kuhl NR, Van Kaer L, Gill RG (2005) Nat Med 11: 1059-65 Class-switched anti-insulin antibodies originate from unconventional antigen presentation in multiple lymphoid sites. Wan X, Thomas JW, Unanue ER (2016) J Exp Med 213: 967-78 B-cell signaling networks reveal a negative prognostic human lymphoma cell subset that emerges during tumor progression. Irish JM, Myklebust JH, Alizadeh AA, Houot R, Sharman JP, Czerwinski DK, Nolan GP, Levy R (2010) Proc Natl Acad Sci U S A 107: 12747-54 Immune responses to abacavir in antigen-presenting cells from hypersensitive patients. Martin AM, Almeida CA, Cameron P, Purcell AW, Nolan D, James I, McCluskey J, Phillips E, Landay A, Mallal S (2007) AIDS 21: 1233-44 Differential regulation of Th1 and Th2 functions of NKT cells by CD28 and CD40 costimulatory pathways. Hayakawa Y, Takeda K, Yagita H, Van Kaer L, Saiki I, Okumura K (2001) J Immunol 166: 6012-8 Reversing Tolerance in Isotype Switch-Competent Anti-Insulin B Lymphocytes. Williams JM, Bonami RH, Hulbert C, Thomas JW (2015) J Immunol 195: 853-64 Prostaglandin I2 analogs inhibit proinflammatory cytokine production and T cell stimulatory function of dendritic cells. Zhou W, Hashimoto K, Goleniewska K, O'Neal JF, Ji S, Blackwell TS, Fitzgerald GA, Egan KM, Geraci MW, Peebles RS (2007) J Immunol 178: 702-10 Functional silencing is initiated and maintained in immature anti-insulin B cells. Henry RA, Acevedo-Suárez CA, Thomas JW (2009) J Immunol 182: 3432-9 Natural killer T cells restricted by the monomorphic MHC class 1b CD1d1 molecules behave like inflammatory cells. Mempel M, Ronet C, Suarez F, Gilleron M, Puzo G, Van Kaer L, Lehuen A, Kourilsky P, Gachelin G (2002) J Immunol 168: 365-71 Altered BCR and CD40 signalling are associated with clinical outcome in small lymphocytic lymphoma/chronic lymphocytic leukaemia and marginal zone lymphoma patients. Blix ES, Irish JM, Husebekk A, Delabie J, Tierens AM, Myklebust JH, Kolstad A (2012) Br J Haematol 159: 604-8 Variants of the CD40 gene but not of the CD40L gene are associated with coronary artery calcification in the Diabetes Heart Study (DHS). Burdon KP, Langefeld CD, Beck SR, Wagenknecht LE, Carr JJ, Rich SS, Freedman BI, Herrington D, Bowden DW (2006) Am Heart J 151: 706-11 Human Germinal Center B Cells Differ from Naïve and Memory B Cells in CD40 Expression and CD40L-Induced Signaling Response. Huse K, Wogsland CE, Polikowsky HG, Diggins KE, Smeland EB, Myklebust JH, Irish JM (2019) Cytometry A 95: 442-449 Agonistic antibody to CD40 boosts the antitumor activity of adoptively transferred T cells in vivo. Liu C, Lewis CM, Lou Y, Xu C, Peng W, Yang Y, Gelbard AH, Lizée G, Zhou D, Overwijk WW, Hwu P (2012) J Immunother 35: 276-82 Phospho-specific flow cytometry identifies aberrant signaling in indolent B-cell lymphoma. Blix ES, Irish JM, Husebekk A, Delabie J, Forfang L, Tierens AM, Myklebust JH, Kolstad A (2012) BMC Cancer 12: 478 The interface between innate and acquired immunity: glycolipid antigen presentation by CD1d-expressing dendritic cells to NKT cells induces the differentiation of antigen-specific cytotoxic T lymphocytes. Nishimura T, Kitamura H, Iwakabe K, Yahata T, Ohta A, Sato M, Takeda K, Okumura K, Van Kaer L, Kawano T, Taniguchi M, Nakui M, Sekimoto M, Koda T (2000) Int Immunol 12: 987-94 CD40-ligand in primate cardiac allograft and viral immunity. Pierson RN, Crowe JE, Pfeiffer S, Atkinson J, Azimzadeh A, Miller GG (2001) Immunol Res 23: 253-62
Hints: (1) double-click or double-tap to navigate to a node. (2) Grab a node and move it to arrange the graph.