Biochemically based design of cyclooxygenase-2 (COX-2) inhibitors: facile conversion of nonsteroidal antiinflammatory drugs to potent and highly selective COX-2 inhibitors. Kalgutkar AS, Crews BC, Rowlinson SW, Marnett AB, Kozak KR, Remmel RP, Marnett LJ (2000) Proc Natl Acad Sci U S A 97: 925-30 Biomarkers of oxidative stress study III. Effects of the nonsteroidal anti-inflammatory agents indomethacin and meclofenamic acid on measurements of oxidative products of lipids in CCl4 poisoning. Kadiiska MB, Gladen BC, Baird DD, Graham LB, Parker CE, Ames BN, Basu S, Fitzgerald GA, Lawson JA, Marnett LJ, Morrow JD, Murray DM, Plastaras J, Roberts LJ, Rokach J, Shigenaga MK, Sun J, Walter PB, Tomer KB, Barrett JC, Mason RP (2005) Free Radic Biol Med 38: 711-8 Amide derivatives of meclofenamic acid as selective cyclooxygenase-2 inhibitors. Kalgutkar AS, Rowlinson SW, Crews BC, Marnett LJ (2002) Bioorg Med Chem Lett 12: 521-4
Hints: (1) double-click or double-tap to navigate to a node. (2) Grab a node and move it to arrange the graph.