Erythrocyte G protein-coupled receptor signaling in malarial infection. Harrison T, Samuel BU, Akompong T, Hamm H, Mohandas N, Lomasney JW, Haldar K (2003) Science 301: 1734-6 Serum neutralizing antibody response to the vacuolating cytotoxin of Helicobacter pylori. Cover TL, Cao P, Murthy UK, Sipple MS, Blaser MJ (1992) J Clin Invest 90: 913-8 Acid-induced dissociation of VacA, the Helicobacter pylori vacuolating cytotoxin, reveals its pattern of assembly. Cover TL, Hanson PI, Heuser JE (1997) J Cell Biol 138: 759-69 SopB promotes phosphatidylinositol 3-phosphate formation on Salmonella vacuoles by recruiting Rab5 and Vps34. Mallo GV, Espina M, Smith AC, Terebiznik MR, Alemán A, Finlay BB, Rameh LE, Grinstein S, Brumell JH (2008) J Cell Biol 182: 741-52 Effects of Helicobacter pylori vacuolating cytotoxin on primary cultures of human gastric epithelial cells. Smoot DT, Resau JH, Earlington MH, Simpson M, Cover TL (1996) Gut 39: 795-9 The m2 form of the Helicobacter pylori cytotoxin has cell type-specific vacuolating activity. Pagliaccia C, de Bernard M, Lupetti P, Ji X, Burroni D, Cover TL, Papini E, Rappuoli R, Telford JL, Reyrat JM (1998) Proc Natl Acad Sci U S A 95: 10212-7 The vacuolating toxin from Helicobacter pylori forms hexameric pores in lipid bilayers at low pH. Czajkowsky DM, Iwamoto H, Cover TL, Shao Z (1999) Proc Natl Acad Sci U S A 96: 2001-6 The auxilin-like phosphoprotein Swa2p is required for clathrin function in yeast. Gall WE, Higginbotham MA, Chen C, Ingram MF, Cyr DM, Graham TR (2000) Curr Biol 10: 1349-58 Cytoplasmic remodeling of erythrocyte raft lipids during infection by the human malaria parasite Plasmodium falciparum. Murphy SC, Fernandez-Pol S, Chung PH, Prasanna Murthy SN, Milne SB, Salomao M, Brown HA, Lomasney JW, Mohandas N, Haldar K (2007) Blood 110: 2132-9 Induction of gastric epithelial cell apoptosis by Helicobacter pylori vacuolating cytotoxin. Cover TL, Krishna US, Israel DA, Peek RM (2003) Cancer Res 63: 951-7 An intracellular target for Helicobacter pylori vacuolating toxin. Cover TL (1998) Trends Microbiol 6: 127-8; discussion 128-9 Bax-inhibiting peptide protects cells from polyglutamine toxicity caused by Ku70 acetylation. Li Y, Yokota T, Gama V, Yoshida T, Gomez JA, Ishikawa K, Sasaguri H, Cohen HY, Sinclair DA, Mizusawa H, Matsuyama S (2007) Cell Death Differ 14: 2058-67 Potentiation of Helicobacter pylori vacuolating toxin activity by nicotine and other weak bases. Cover TL, Vaughn SG, Cao P, Blaser MJ (1992) J Infect Dis 166: 1073-8 Helicobacter pylori vacuolating cytotoxin inhibits activation-induced proliferation of human T and B lymphocyte subsets. Torres VJ, VanCompernolle SE, Sundrud MS, Unutmaz D, Cover TL (2007) J Immunol 179: 5433-40 Tapasin-/- and TAP1-/- macrophages are deficient in vacuolar alternate class I MHC (MHC-I) processing due to decreased MHC-I stability at phagolysosomal pH. Chefalo PJ, Grandea AG, Van Kaer L, Harding CV (2003) J Immunol 170: 5825-33 Structural organization of membrane-inserted hexamers formed by Helicobacter pylori VacA toxin. Pyburn TM, Foegeding NJ, González-Rivera C, McDonald NA, Gould KL, Cover TL, Ohi MD (2016) Mol Microbiol 102: 22-36 Acid activation of Helicobacter pylori vacuolating cytotoxin (VacA) results in toxin internalization by eukaryotic cells. McClain MS, Schraw W, Ricci V, Boquet P, Cover TL (2000) Mol Microbiol 37: 433-42 Alteration of epithelial structure and function associated with PtdIns(4,5)P2 degradation by a bacterial phosphatase. Mason D, Mallo GV, Terebiznik MR, Payrastre B, Finlay BB, Brumell JH, Rameh L, Grinstein S (2007) J Gen Physiol 129: 267-83 Cell vacuolation induced by the VacA cytotoxin of Helicobacter pylori is regulated by the Rac1 GTPase. Hotchin NA, Cover TL, Akhtar N (2000) J Biol Chem 275: 14009-12 A dominant negative mutant of Helicobacter pylori vacuolating toxin (VacA) inhibits VacA-induced cell vacuolation. Vinion-Dubiel AD, McClain MS, Czajkowsky DM, Iwamoto H, Ye D, Cao P, Schraw W, Szabo G, Blanke SR, Shao Z, Cover TL (1999) J Biol Chem 274: 37736-42 Cellular vacuolation and mitochondrial cytochrome c release are independent outcomes of Helicobacter pylori vacuolating cytotoxin activity that are each dependent on membrane channel formation. Willhite DC, Cover TL, Blanke SR (2003) J Biol Chem 278: 48204-9 Association of Helicobacter pylori vacuolating toxin (VacA) with lipid rafts. Schraw W, Li Y, McClain MS, van der Goot FG, Cover TL (2002) J Biol Chem 277: 34642-50 Requirement for neo1p in retrograde transport from the Golgi complex to the endoplasmic reticulum. Hua Z, Graham TR (2003) Mol Biol Cell 14: 4971-83 Clustering and redistribution of late endocytic compartments in response to Helicobacter pylori vacuolating toxin. Li Y, Wandinger-Ness A, Goldenring JR, Cover TL (2004) Mol Biol Cell 15: 1946-59 Control of protein and sterol trafficking by antagonistic activities of a type IV P-type ATPase and oxysterol binding protein homologue. Muthusamy BP, Raychaudhuri S, Natarajan P, Abe F, Liu K, Prinz WA, Graham TR (2009) Mol Biol Cell 20: 2920-31 An essential subfamily of Drs2p-related P-type ATPases is required for protein trafficking between Golgi complex and endosomal/vacuolar system. Hua Z, Fatheddin P, Graham TR (2002) Mol Biol Cell 13: 3162-77 Sorting of yeast alpha 1,3 mannosyltransferase is mediated by a lumenal domain interaction, and a transmembrane domain signal that can confer clathrin-dependent Golgi localization to a secreted protein. Graham TR, Krasnov VA (1995) Mol Biol Cell 6: 809-24 Shear stress induces noncanonical autophagy in intestinal epithelial monolayers. Kim SW, Ehrman J, Ahn MR, Kondo J, Lopez AAM, Oh YS, Kim XH, Crawley SW, Goldenring JR, Tyska MJ, Rericha EC, Lau KS (2017) Mol Biol Cell 28: 3043-3056 An arf1Delta synthetic lethal screen identifies a new clathrin heavy chain conditional allele that perturbs vacuolar protein transport in Saccharomyces cerevisiae. Chen CY, Graham TR (1998) Genetics 150: 577-89 Mapping of a domain required for protein-protein interactions and inhibitory activity of a Helicobacter pylori dominant-negative VacA mutant protein. Torres VJ, McClain MS, Cover TL (2006) Infect Immun 74: 2093-101 Helicobacter pylori cytotoxin induces vacuolation of primary human mucosal epithelial cells. Harris PR, Cover TL, Crowe DR, Orenstein JM, Graham MF, Blaser MJ, Smith PD (1996) Infect Immun 64: 4867-71 Characteristics of Helicobacter pylori variants selected for urease deficiency. Pérez-Pérez GI, Olivares AZ, Cover TL, Blaser MJ (1992) Infect Immun 60: 3658-63 Effects of ATPase inhibitors on the response of HeLa cells to Helicobacter pylori vacuolating toxin. Cover TL, Reddy LY, Blaser MJ (1993) Infect Immun 61: 1427-31 Determinants of Raft Partitioning of the Helicobacter pylori Pore-Forming Toxin VacA. Raghunathan K, Foegeding NJ, Campbell AM, Cover TL, Ohi MD, Kenworthy AK (2018) Infect Immun 86: Characterization of and human serologic response to proteins in Helicobacter pylori broth culture supernatants with vacuolizing cytotoxin activity. Cover TL, Dooley CP, Blaser MJ (1990) Infect Immun 58: 603-10 Functional Properties of Helicobacter pylori VacA Toxin m1 and m2 Variants. Caston RR, Sierra JC, Foegeding NJ, Truelock MD, Campbell AM, Frick-Cheng AE, Bimczok D, Wilson KT, McClain MS, Cover TL (2020) Infect Immun 88: Random mutagenesis of Helicobacter pylori vacA to identify amino acids essential for vacuolating cytotoxic activity. McClain MS, Czajkowsky DM, Torres VJ, Szabo G, Shao Z, Cover TL (2006) Infect Immun 74: 6188-95 Effect of urease on HeLa cell vacuolation induced by Helicobacter pylori cytotoxin. Cover TL, Puryear W, Perez-Perez GI, Blaser MJ (1991) Infect Immun 59: 1264-70 Multiple oligomeric states of the Helicobacter pylori vacuolating toxin demonstrated by cryo-electron microscopy. Adrian M, Cover TL, Dubochet J, Heuser JE (2002) J Mol Biol 318: 121-33 The C/EBPbeta isoform, liver-inhibitory protein (LIP), induces autophagy in breast cancer cell lines. Abreu MM, Sealy L (2010) Exp Cell Res 316: 3227-38
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