Cardiomyocyte-restricted overexpression of endothelial nitric oxide synthase (NOS3) attenuates beta-adrenergic stimulation and reinforces vagal inhibition of cardiac contraction. Massion PB, Dessy C, Desjardins F, Pelat M, Havaux X, Belge C, Moulin P, Guiot Y, Feron O, Janssens S, Balligand JL (2004) Circulation 110: 2666-72 Peering inside lipid rafts and caveolae. Kenworthy A (2002) Trends Biochem Sci 27: 435-7 Novel role of ARF6 in vascular endothelial growth factor-induced signaling and angiogenesis. Ikeda S, Ushio-Fukai M, Zuo L, Tojo T, Dikalov S, Patrushev NA, Alexander RW (2005) Circ Res 96: 467-75 Integrin alpha1beta1 regulates epidermal growth factor receptor activation by controlling peroxisome proliferator-activated receptor gamma-dependent caveolin-1 expression. Chen X, Whiting C, Borza C, Hu W, Mont S, Bulus N, Zhang MZ, Harris RC, Zent R, Pozzi A (2010) Mol Cell Biol 30: 3048-58 Coordinate regulation of L-arginine uptake and nitric oxide synthase activity in cultured endothelial cells. Hardy TA, May JM (2002) Free Radic Biol Med 32: 122-31 Characterization of a caveolin-1 mutation associated with both pulmonary arterial hypertension and congenital generalized lipodystrophy. Han B, Copeland CA, Kawano Y, Rosenzweig EB, Austin ED, Shahmirzadi L, Tang S, Raghunathan K, Chung WK, Kenworthy AK (2016) Traffic 17: 1297-1312 Heterozygous null bone morphogenetic protein receptor type 2 mutations promote SRC kinase-dependent caveolar trafficking defects and endothelial dysfunction in pulmonary arterial hypertension. Prewitt AR, Ghose S, Frump AL, Datta A, Austin ED, Kenworthy AK, de Caestecker MP (2015) J Biol Chem 290: 960-71 A disease-associated frameshift mutation in caveolin-1 disrupts caveolae formation and function through introduction of a de novo ER retention signal. Copeland CA, Han B, Tiwari A, Austin ED, Loyd JE, West JD, Kenworthy AK (2017) Mol Biol Cell 28: 3095-3111 Internalization and intracellular trafficking of a PTD-conjugated anti-fibrotic peptide, AZX100, in human dermal keloid fibroblasts. Flynn CR, Cheung-Flynn J, Smoke CC, Lowry D, Roberson R, Sheller MR, Brophy CM (2010) J Pharm Sci 99: 3100-21
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