The molecular evolution of acquired resistance to targeted EGFR blockade in colorectal cancers. Diaz LA, Williams RT, Wu J, Kinde I, Hecht JR, Berlin J, Allen B, Bozic I, Reiter JG, Nowak MA, Kinzler KW, Oliner KS, Vogelstein B (2012) Nature 486: 537-40 Non-optimal codon usage is a mechanism to achieve circadian clock conditionality. Xu Y, Ma P, Shah P, Rokas A, Liu Y, Johnson CH (2013) Nature 495: 116-20 Evolutionary flux of canonical microRNAs and mirtrons in Drosophila. Berezikov E, Liu N, Flynt AS, Hodges E, Rooks M, Hannon GJ, Lai EC (2010) Nat Genet 42: 6-9; author reply 9-10 Identifying -mediators for -eQTLs across many human tissues using genomic mediation analysis. Yang F, Wang J, GTEx Consortium, Pierce BL, Chen LS (2017) Genome Res 27: 1859-1871 Selection against pathogenic mtDNA mutations in a stem cell population leads to the loss of the 3243A-->G mutation in blood. Rajasimha HK, Chinnery PF, Samuels DC (2008) Am J Hum Genet 82: 333-43 Genomic Characterization of Esophageal Squamous Cell Carcinoma Reveals Critical Genes Underlying Tumorigenesis and Poor Prognosis. Qin HD, Liao XY, Chen YB, Huang SY, Xue WQ, Li FF, Ge XS, Liu DQ, Cai Q, Long J, Li XZ, Hu YZ, Zhang SD, Zhang LJ, Lehrman B, Scott AF, Lin D, Zeng YX, Shugart YY, Jia WH (2016) Am J Hum Genet 98: 709-27 Comparing phylogeny and the predicted pathogenicity of protein variations reveals equal purifying selection across the global human mtDNA diversity. Pereira L, Soares P, Radivojac P, Li B, Samuels DC (2011) Am J Hum Genet 88: 433-9 Geographic and haplotype structure of candidate type 2 diabetes susceptibility variants at the calpain-10 locus. Fullerton SM, Bartoszewicz A, Ybazeta G, Horikawa Y, Bell GI, Kidd KK, Cox NJ, Hudson RR, Di Rienzo A (2002) Am J Hum Genet 70: 1096-106 Shared Selective Pressures on Fungal and Human Metabolic Pathways Lead to Divergent yet Analogous Genetic Responses. Eidem HR, McGary KL, Rokas A (2015) Mol Biol Evol 32: 1449-55 Evidence for variable selective pressures at a large secondary structure of the human mitochondrial DNA control region. Pereira F, Soares P, Carneiro J, Pereira L, Richards MB, Samuels DC, Amorim A (2008) Mol Biol Evol 25: 2759-70 The inheritance of mitochondrial DNA heteroplasmy: random drift, selection or both? Chinnery PF, Thorburn DR, Samuels DC, White SL, Dahl HM, Turnbull DM, Lightowlers RN, Howell N (2000) Trends Genet 16: 500-5 Dual selection mechanisms drive efficient single-gene reverse genetics for rotavirus. Trask SD, Taraporewala ZF, Boehme KW, Dermody TS, Patton JT (2010) Proc Natl Acad Sci U S A 107: 18652-7 The immunopathogenesis of sepsis in elderly patients. Opal SM, Girard TD, Ely EW (2005) Clin Infect Dis 41 Suppl 7: S504-12 The evolution of the human genome. Simonti CN, Capra JA (2015) Curr Opin Genet Dev 35: 9-15 Fine Time Scaling of Purifying Selection on Human Nonsynonymous mtDNA Mutations Based on the Worldwide Population Tree and Mother-Child Pairs. Cavadas B, Soares P, Camacho R, Brandão A, Costa MD, Fernandes V, Pereira JB, Rito T, Samuels DC, Pereira L (2015) Hum Mutat 36: 1100-11 Compensatory substitutions in the HIV-1 capsid reduce the fitness cost associated with resistance to a capsid-targeting small-molecule inhibitor. Shi J, Zhou J, Halambage UD, Shah VB, Burse MJ, Wu H, Blair WS, Butler SL, Aiken C (2015) J Virol 89: 208-19 A Genome-Scale Investigation of Incongruence in Culicidae Mosquitoes. Wang Y, Zhou X, Yang D, Rokas A (2015) Genome Biol Evol 7: 3463-71 Haplotype structure and phylogenetic shadowing of a hypervariable region in the CAPN10 gene. Clark VJ, Cox NJ, Hammond M, Hanis CL, Di Rienzo A (2005) Hum Genet 117: 258-66 Targeted resequencing of a genomic region influencing tameness and aggression reveals multiple signals of positive selection. Albert FW, Hodges E, Jensen JD, Besnier F, Xuan Z, Rooks M, Bhattacharjee A, Brizuela L, Good JM, Green RE, Burbano HA, Plyusnina IZ, Trut L, Andersson L, Schöneberg T, Carlborg O, Hannon GJ, Pääbo S (2011) Heredity (Edinb) 107: 205-14 Evolutionary genomics of a temperate bacteriophage in an obligate intracellular bacteria (Wolbachia). Kent BN, Funkhouser LJ, Setia S, Bordenstein SR (2011) PLoS One 6: e24984 Comparative genomic analysis of East Asian and non-Asian Helicobacter pylori strains identifies rapidly evolving genes. Duncan SS, Valk PL, McClain MS, Shaffer CL, Metcalf JA, Bordenstein SR, Cover TL (2013) PLoS One 8: e55120 Is selection required for the accumulation of somatic mitochondrial DNA mutations in post-mitotic cells? Durham SE, Samuels DC, Chinnery PF (2006) Neuromuscul Disord 16: 381-6 Somatic mitochondrial DNA mutations in cancer escape purifying selection and high pathogenicity mutations lead to the oncocytic phenotype: pathogenicity analysis of reported somatic mtDNA mutations in tumors. Pereira L, Soares P, Máximo V, Samuels DC (2012) BMC Cancer 12: 53 A new lysozyme from the eastern oyster, Crassostrea virginica, and a possible evolutionary pathway for i-type lysozymes in bivalves from host defense to digestion. Xue Q, Hellberg ME, Schey KL, Itoh N, Eytan RI, Cooper RK, La Peyre JF (2010) BMC Evol Biol 10: 213 Construction of an alkaline phosphatase fusion-generating transposon, mTn10phoA. McClain MS, Engleberg NC (1996) Gene 170: 147-8 Body weight gain is correlated with serum cholesterol at 8 weeks of age in pigs selected for four generations for low or high serum cholesterol. Pond WG, Mersmann HJ, Klein PD, Ferlic LL, Wong WW, Hachey DL, Schoknecht PA, Zhang S (1993) J Anim Sci 71: 2406-11 Examination of Signatures of Recent Positive Selection on Genes Involved in Human Sialic Acid Biology. Moon JM, Aronoff DM, Capra JA, Abbot P, Rokas A (2018) G3 (Bethesda) 8: 1315-1325 The ontogeny of delta-like protein 1 messenger ribonucleic acid expression during muscle development and regeneration: comparison of broiler and Leghorn chickens. Shin J, Velleman SG, Latshaw JD, Wick MP, Suh Y, Lee K (2009) Poult Sci 88: 1427-37
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