Keyword Connections

•  Maciej Buchowski

•  Vance Albaugh

Resources

• Energy Balance Services
• Energy Balance Sub-Core

Communities

• No matching connections

Publications

• G-protein-independent coupling of MC4R to Kir7.1 in hypothalamic neurons.
  Ghamari-Langroudi M, Digby GJ, Sebag JA, Millhauser GL, Palomino R, Matthews R, Gillyard T, Panaro BL, Tough IR, Cox HM, Denton JS, Cone RD
  (2015) Nature 520: 94-8
• Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity.
  Turcot V, Lu Y, Highland HM, Schurmann C, Justice AE, Fine RS, Bradfield JP, Esko T, Giri A, Graff M, Guo X, Hendricks AE, Karaderi T, Lempradl A, Locke AE, Mahajan A, Marouli E, Sivapalaratnam S, Young KL, Alfred T, Feitosa MF, Masca NGD, Manning AK, Medina-Gomez C, Mudgal P, Ng MCY, Reiner AP, Vedantam S, Willems SM, Winkler TW, Abecasis G, Aben KK, Alam DS, Alharthi SE, Allison M, Amouyel P, Asselbergs FW, Auer PL, Balkau B, Bang LE, Barroso I, Bastarache L, Benn M, Bergmann S, Bielak LF, Blüher M, Boehnke M, Boeing H, Boerwinkle E, Böger CA, Bork-Jensen J, Bots ML, Bottinger EP, Bowden DW, Brandslund I, Breen G, Brilliant MH, Broer L, Brumat M, Burt AA, Butterworth AS, Campbell PT, Cappellani S, Carey DJ, Catamo E, Caulfield MJ, Chambers JC, Chasman DI, Chen YI, Chowdhury R, Christensen C, Chu AY, Cocca M, Collins FS, Cook JP, Corley J, Corominas Galbany J, Cox AJ, Crosslin DS, Cuellar-Partida G, D'Eustacchio A, Danesh J, Davies G, Bakker PIW, Groot MCH, Mutsert R, Deary IJ, Dedoussis G, Demerath EW, Heijer M, Hollander AI, Ruijter HM, Dennis JG, Denny JC, Di Angelantonio E, Drenos F, Du M, Dubé MP, Dunning AM, Easton DF, Edwards TL, Ellinghaus D, Ellinor PT, Elliott P, Evangelou E, Farmaki AE, Farooqi IS, Faul JD, Fauser S, Feng S, Ferrannini E, Ferrieres J, Florez JC, Ford I, Fornage M, Franco OH, Franke A, Franks PW, Friedrich N, Frikke-Schmidt R, Galesloot TE, Gan W, Gandin I, Gasparini P, Gibson J, Giedraitis V, Gjesing AP, Gordon-Larsen P, Gorski M, Grabe HJ, Grant SFA, Grarup N, Griffiths HL, Grove ML, Gudnason V, Gustafsson S, Haessler J, Hakonarson H, Hammerschlag AR, Hansen T, Harris KM, Harris TB, Hattersley AT, Have CT, Hayward C, He L, Heard-Costa NL, Heath AC, Heid IM, Helgeland Ø, Hernesniemi J, Hewitt AW, Holmen OL, Hovingh GK, Howson JMM, Hu Y, Huang PL, Huffman JE, Ikram MA, Ingelsson E, Jackson AU, Jansson JH, Jarvik GP, Jensen GB, Jia Y, Johansson S, Jørgensen ME, Jørgensen T, Jukema JW, Kahali B, Kahn RS, Kähönen M, Kamstrup PR, Kanoni S, Kaprio J, Karaleftheri M, Kardia SLR, Karpe F, Kathiresan S, Kee F, Kiemeney LA, Kim E, Kitajima H, Komulainen P, Kooner JS, Kooperberg C, Korhonen T, Kovacs P, Kuivaniemi H, Kutalik Z, Kuulasmaa K, Kuusisto J, Laakso M, Lakka TA, Lamparter D, Lange EM, Lange LA, Langenberg C, Larson EB, Lee NR, Lehtimäki T, Lewis CE, Li H, Li J, Li-Gao R, Lin H, Lin KH, Lin LA, Lin X, Lind L, Lindström J, Linneberg A, Liu CT, Liu DJ, Liu Y, Lo KS, Lophatananon A, Lotery AJ, Loukola A, Luan J, Lubitz SA, Lyytikäinen LP, Männistö S, Marenne G, Mazul AL, McCarthy MI, McKean-Cowdin R, Medland SE, Meidtner K, Milani L, Mistry V, Mitchell P, Mohlke KL, Moilanen L, Moitry M, Montgomery GW, Mook-Kanamori DO, Moore C, Mori TA, Morris AD, Morris AP, Müller-Nurasyid M, Munroe PB, Nalls MA, Narisu N, Nelson CP, Neville M, Nielsen SF, Nikus K, Njølstad PR, Nordestgaard BG, Nyholt DR, O'Connel JR, O'Donoghue ML, Olde Loohuis LM, Ophoff RA, Owen KR, Packard CJ, Padmanabhan S, Palmer CNA, Palmer ND, Pasterkamp G, Patel AP, Pattie A, Pedersen O, Peissig PL, Peloso GM, Pennell CE, Perola M, Perry JA, Perry JRB, Pers TH, Person TN, Peters A, Petersen ERB, Peyser PA, Pirie A, Polasek O, Polderman TJ, Puolijoki H, Raitakari OT, Rasheed A, Rauramaa R, Reilly DF, Renström F, Rheinberger M, Ridker PM, Rioux JD, Rivas MA, Roberts DJ, Robertson NR, Robino A, Rolandsson O, Rudan I, Ruth KS, Saleheen D, Salomaa V, Samani NJ, Sapkota Y, Sattar N, Schoen RE, Schreiner PJ, Schulze MB, Scott RA, Segura-Lepe MP, Shah SH, Sheu WH, Sim X, Slater AJ, Small KS, Smith AV, Southam L, Spector TD, Speliotes EK, Starr JM, Stefansson K, Steinthorsdottir V, Stirrups KE, Strauch K, Stringham HM, Stumvoll M, Sun L, Surendran P, Swift AJ, Tada H, Tansey KE, Tardif JC, Taylor KD, Teumer A, Thompson DJ, Thorleifsson G, Thorsteinsdottir U, Thuesen BH, Tönjes A, Tromp G, Trompet S, Tsafantakis E, Tuomilehto J, Tybjaerg-Hansen A, Tyrer JP, Uher R, Uitterlinden AG, Uusitupa M, Laan SW, Duijn CM, Leeuwen N, van Setten J, Vanhala M, Varbo A, Varga TV, Varma R, Velez Edwards DR, Vermeulen SH, Veronesi G, Vestergaard H, Vitart V, Vogt TF, Völker U, Vuckovic D, Wagenknecht LE, Walker M, Wallentin L, Wang F, Wang CA, Wang S, Wang Y, Ware EB, Wareham NJ, Warren HR, Waterworth DM, Wessel J, White HD, Willer CJ, Wilson JG, Witte DR, Wood AR, Wu Y, Yaghootkar H, Yao J, Yao P, Yerges-Armstrong LM, Young R, Zeggini E, Zhan X, Zhang W, Zhao JH, Zhao W, Zhao W, Zhou W, Zondervan KT, CHD Exome+ Consortium, EPIC-CVD Consortium, ExomeBP Consortium, Global Lipids Genetic Consortium, GoT2D Genes Consortium, EPIC InterAct Consortium, INTERVAL Study, ReproGen Consortium, T2D-Genes Consortium, MAGIC Investigators, Understanding Society Scientific Group, Rotter JI, Pospisilik JA, Rivadeneira F, Borecki IB, Deloukas P, Frayling TM, Lettre G, North KE, Lindgren CM, Hirschhorn JN, Loos RJF
  (2018) Nat Genet 50: 26-41
• The protein kinase IKKepsilon regulates energy balance in obese mice.
  Chiang SH, Bazuine M, Lumeng CN, Geletka LM, Mowers J, White NM, Ma JT, Zhou J, Qi N, Westcott D, Delproposto JB, Blackwell TS, Yull FE, Saltiel AR
  (2009) Cell 138: 961-75
• Human Semaphorin 3 Variants Link Melanocortin Circuit Development and Energy Balance.
  van der Klaauw AA, Croizier S, Mendes de Oliveira E, Stadler LKJ, Park S, Kong Y, Banton MC, Tandon P, Hendricks AE, Keogh JM, Riley SE, Papadia S, Henning E, Bounds R, Bochukova EG, Mistry V, O'Rahilly S, Simerly RB, INTERVAL, UK10K Consortium, Minchin JEN, Barroso I, Jones EY, Bouret SG, Farooqi IS
  (2019) Cell 176: 729-742.e18
• HIF-1alpha is essential for myeloid cell-mediated inflammation.
  Cramer T, Yamanishi Y, Clausen BE, Förster I, Pawlinski R, Mackman N, Haase VH, Jaenisch R, Corr M, Nizet V, Firestein GS, Gerber HP, Ferrara N, Johnson RS
  (2003) Cell 112: 645-57
• Systemic elevation of PTEN induces a tumor-suppressive metabolic state.
  Garcia-Cao I, Song MS, Hobbs RM, Laurent G, Giorgi C, de Boer VC, Anastasiou D, Ito K, Sasaki AT, Rameh L, Carracedo A, Vander Heiden MG, Cantley LC, Pinton P, Haigis MC, Pandolfi PP
  (2012) Cell 149: 49-62
• Neuronal pathway from the liver modulates energy expenditure and systemic insulin sensitivity.
  Uno K, Katagiri H, Yamada T, Ishigaki Y, Ogihara T, Imai J, Hasegawa Y, Gao J, Kaneko K, Iwasaki H, Ishihara H, Sasano H, Inukai K, Mizuguchi H, Asano T, Shiota M, Nakazato M, Oka Y
  (2006) Science 312: 1656-9
• Developmental control of the melanocortin-4 receptor by MRAP2 proteins in zebrafish.
  Sebag JA, Zhang C, Hinkle PM, Bradshaw AM, Cone RD
  (2013) Science 341: 278-81
• Effects of dietary composition on energy expenditure during weight-loss maintenance.
  Ebbeling CB, Swain JF, Feldman HA, Wong WW, Hachey DL, Garcia-Lago E, Ludwig DS
  (2012) JAMA 307: 2627-34
• Beta-adrenergic receptors and regulation of energy expenditure: a family affair.
  Robidoux J, Martin TL, Collins S
  (2004) Annu Rev Pharmacol Toxicol 44: 297-323
• Light-dependent redistribution of arrestin in vertebrate rods is an energy-independent process governed by protein-protein interactions.
  Nair KS, Hanson SM, Mendez A, Gurevich EV, Kennedy MJ, Shestopalov VI, Vishnivetskiy SA, Chen J, Hurley JB, Gurevich VV, Slepak VZ
  (2005) Neuron 46: 555-67
• Anatomy and regulation of the central melanocortin system.
  Cone RD
  (2005) Nat Neurosci 8: 571-8
• Cholecystokinin-mediated suppression of feeding involves the brainstem melanocortin system.
  Fan W, Ellacott KL, Halatchev IG, Takahashi K, Yu P, Cone RD
  (2004) Nat Neurosci 7: 335-6
• Olanzapine promotes fat accumulation in male rats by decreasing physical activity, repartitioning energy and increasing adipose tissue lipogenesis while impairing lipolysis.
  Albaugh VL, Judson JG, She P, Lang CH, Maresca KP, Joyal JL, Lynch CJ
  (2011) Mol Psychiatry 16: 569-81
• CalR: A Web-Based Analysis Tool for Indirect Calorimetry Experiments.
  Mina AI, LeClair RA, LeClair KB, Cohen DE, Lantier L, Banks AS
  (2018) Cell Metab 28: 656-666.e1
• Cytosolic phosphoenolpyruvate carboxykinase does not solely control the rate of hepatic gluconeogenesis in the intact mouse liver.
  Burgess SC, He T, Yan Z, Lindner J, Sherry AD, Malloy CR, Browning JD, Magnuson MA
  (2007) Cell Metab 5: 313-20
• Differences in lymphocyte electron transport gene expression levels between subjects with bipolar disorder and normal controls in response to glucose deprivation stress.
  Naydenov AV, MacDonald ML, Ongur D, Konradi C
  (2007) Arch Gen Psychiatry 64: 555-64
• High salt intake reprioritizes osmolyte and energy metabolism for body fluid conservation.
  Kitada K, Daub S, Zhang Y, Klein JD, Nakano D, Pedchenko T, Lantier L, LaRocque LM, Marton A, Neubert P, Schröder A, Rakova N, Jantsch J, Dikalova AE, Dikalov SI, Harrison DG, Müller DN, Nishiyama A, Rauh M, Harris RC, Luft FC, Wassermann DH, Sands JM, Titze J
  (2017) J Clin Invest 127: 1944-1959
• Serotonin 2C receptors in pro-opiomelanocortin neurons regulate energy and glucose homeostasis.
  Berglund ED, Liu C, Sohn JW, Liu T, Kim MH, Lee CE, Vianna CR, Williams KW, Xu Y, Elmquist JK
  (2013) J Clin Invest 123: 5061-70
• Intradialytic parenteral nutrition improves protein and energy homeostasis in chronic hemodialysis patients.
  Pupim LB, Flakoll PJ, Brouillette JR, Levenhagen DK, Hakim RM, Ikizler TA
  (2002) J Clin Invest 110: 483-92
• Hepatic energy state is regulated by glucagon receptor signaling in mice.
  Berglund ED, Lee-Young RS, Lustig DG, Lynes SE, Donahue EP, Camacho RC, Meredith ME, Magnuson MA, Charron MJ, Wasserman DH
  (2009) J Clin Invest 119: 2412-22
• Focal energy deprivation underlies arrhythmia susceptibility in mice with calcium-sensitized myofilaments.
  Huke S, Venkataraman R, Faggioni M, Bennuri S, Hwang HS, Baudenbacher F, Knollmann BC
  (2013) Circ Res 112: 1334-44
• Telomeres and mitochondria in the aging heart.
  Moslehi J, DePinho RA, Sahin E
  (2012) Circ Res 110: 1226-37
• A heart-adipose tissue connection in the regulation of energy metabolism.
  Collins S
  (2014) Nat Rev Endocrinol 10: 157-63
• Integrin cytoplasmic domains mediate inside-out signal transduction.
  O'Toole TE, Katagiri Y, Faull RJ, Peter K, Tamura R, Quaranta V, Loftus JC, Shattil SJ, Ginsberg MH
  (1994) J Cell Biol 124: 1047-59
• Metabolic signatures of exercise in human plasma.
  Lewis GD, Farrell L, Wood MJ, Martinovic M, Arany Z, Rowe GC, Souza A, Cheng S, McCabe EL, Yang E, Shi X, Deo R, Roth FP, Asnani A, Rhee EP, Systrom DM, Semigran MJ, Vasan RS, Carr SA, Wang TJ, Sabatine MS, Clish CB, Gerszten RE
  (2010) Sci Transl Med 2: 33ra37
• Bile diversion to the distal small intestine has comparable metabolic benefits to bariatric surgery.
  Flynn CR, Albaugh VL, Cai S, Cheung-Flynn J, Williams PE, Brucker RM, Bordenstein SR, Guo Y, Wasserman DH, Abumrad NN
  (2015) Nat Commun 6: 7715
• Impaired thermogenesis and adipose tissue development in mice with fat-specific disruption of insulin and IGF-1 signalling.
  Boucher J, Mori MA, Lee KY, Smyth G, Liew CW, Macotela Y, Rourk M, Bluher M, Russell SJ, Kahn CR
  (2012) Nat Commun 3: 902
• Fine tuning of immunometabolism for the treatment of rheumatic diseases.
  Rhoads JP, Major AS, Rathmell JC
  (2017) Nat Rev Rheumatol 13: 313-320
• Melanocortin-3 receptor regulates the normal fasting response.
  Renquist BJ, Murphy JG, Larson EA, Olsen D, Klein RF, Ellacott KL, Cone RD
  (2012) Proc Natl Acad Sci U S A 109: E1489-98
• Multinodal regulation of the arcuate/paraventricular nucleus circuit by leptin.
  Ghamari-Langroudi M, Srisai D, Cone RD
  (2011) Proc Natl Acad Sci U S A 108: 355-60
• Energetic regulation of coordinated leader-follower dynamics during collective invasion of breast cancer cells.
  Zhang J, Goliwas KF, Wang W, Taufalele PV, Bordeleau F, Reinhart-King CA
  (2019) Proc Natl Acad Sci U S A 116: 7867-7872
• Deletion of PPARgamma in adipose tissues of mice protects against high fat diet-induced obesity and insulin resistance.
  Jones JR, Barrick C, Kim KA, Lindner J, Blondeau B, Fujimoto Y, Shiota M, Kesterson RA, Kahn BB, Magnuson MA
  (2005) Proc Natl Acad Sci U S A 102: 6207-12
• Lactate rise detected by 1H NMR in human visual cortex during physiologic stimulation.
  Prichard J, Rothman D, Novotny E, Petroff O, Kuwabara T, Avison M, Howseman A, Hanstock C, Shulman R
  (1991) Proc Natl Acad Sci U S A 88: 5829-31
• The liver.
  Trefts E, Gannon M, Wasserman DH
  (2017) Curr Biol 27: R1147-R1151
• Results of bariatric surgery.
  Hansen EN, Torquati A, Abumrad NN
  (2006) Annu Rev Nutr 26: 481-511
• Metabolic approaches to cancer cachexia.
  Lawson DH, Richmond A, Nixon DW, Rudman D
  (1982) Annu Rev Nutr 2: 277-301
• Increased energy expenditure in hemodialysis patients.
  Ikizler TA, Wingard RL, Sun M, Harvell J, Parker RA, Hakim RM
  (1996) J Am Soc Nephrol 7: 2646-53
• Insulin and its evolving partnership with leptin in the hypothalamic control of energy homeostasis.
  Niswender KD, Baskin DG, Schwartz MW
  (2004) Trends Endocrinol Metab 15: 362-9
• Atypical antipsychotics rapidly and inappropriately switch peripheral fuel utilization to lipids, impairing metabolic flexibility in rodents.
  Albaugh VL, Vary TC, Ilkayeva O, Wenner BR, Maresca KP, Joyal JL, Breazeale S, Elich TD, Lang CH, Lynch CJ
  (2012) Schizophr Bull 38: 153-66