Impairment of T-cell-dependent B-cell responses and B-1 cell development in CD19-deficient mice. Rickert RC, Rajewsky K, Roes J (1995) Nature 376: 352-5 H2-M mutant mice are defective in the peptide loading of class II molecules, antigen presentation, and T cell repertoire selection. Martin WD, Hicks GG, Mendiratta SK, Leva HI, Ruley HE, Van Kaer L (1996) Cell 84: 543-50 Complex N-glycan number and degree of branching cooperate to regulate cell proliferation and differentiation. Lau KS, Partridge EA, Grigorian A, Silvescu CI, Reinhold VN, Demetriou M, Dennis JW (2007) Cell 129: 123-34 The human invariant chain is the core protein of the human class II-associated proteoglycan. Giacoletto KS, Sant AJ, Bono C, Gorka J, O'Sullivan DM, Quaranta V, Schwartz BD (1986) J Exp Med 164: 1422-39 H2-DMalpha(-/-) mice show the importance of major histocompatibility complex-bound peptide in cardiac allograft rejection. Felix NJ, Brickey WJ, Griffiths R, Zhang J, Van Kaer L, Coffman T, Ting JP (2000) J Exp Med 192: 31-40 Invariant chain-independent function of H-2M in the formation of endogenous peptide-major histocompatibility complex class II complexes in vivo. Kovats S, Grubin CE, Eastman S, deRoos P, Dongre A, Van Kaer L, Rudensky AY (1998) J Exp Med 187: 245-51 Recognition of MHC TL gene products by gamma delta T cells. Van Kaer L, Wu M, Ichikawa Y, Ito K, Bonneville M, Ostrand-Rosenberg S, Murphy DB, Tonegawa S (1991) Immunol Rev 120: 89-115 Impaired T-cell receptor activation in IL-1 receptor-associated kinase-4-deficient patients. McDonald DR, Goldman F, Gomez-Duarte OD, Issekutz AC, Kumararatne DS, Doffinger R, Geha RS (2010) J Allergy Clin Immunol 126: 332-7, 337.e1-2 Cell-free pool of CD14 mediates activation of transcription factor NF-kappa B by lipopolysaccharide in human endothelial cells. Read MA, Cordle SR, Veach RA, Carlisle CD, Hawiger J (1993) Proc Natl Acad Sci U S A 90: 9887-91 CD318 is a ligand for CD6. Enyindah-Asonye G, Li Y, Ruth JH, Spassov DS, Hebron KE, Zijlstra A, Moasser MM, Wang B, Singer NG, Cui H, Ohara RA, Rasmussen SM, Fox DA, Lin F (2017) Proc Natl Acad Sci U S A 114: E6912-E6921 NKT cell costimulation: experimental progress and therapeutic promise. van den Heuvel MJ, Garg N, Van Kaer L, Haeryfar SM (2011) Trends Mol Med 17: 65-77 The human myeloid cell nuclear differentiation antigen gene is one of at least two related interferon-inducible genes located on chromosome 1q that are expressed specifically in hematopoietic cells. Briggs RC, Briggs JA, Ozer J, Sealy L, Dworkin LL, Kingsmore SF, Seldin MF, Kaur GP, Athwal RS, Dessypris EN (1994) Blood 83: 2153-62 Leukemia inhibitory factor upregulates cytokine expression by a murine stromal cell line enabling the maintenance of highly enriched competitive repopulating stem cells. Szilvassy SJ, Weller KP, Lin W, Sharma AK, Ho AS, Tsukamoto A, Hoffman R, Leiby KR, Gearing DP (1996) Blood 87: 4618-28 Antigen-specific recognition of autologous leukemia cells and allogeneic class-I MHC antigens by IL-2-activated cytotoxic T cells from a patient with acute T-cell leukemia. Fisch P, Weil-Hillman G, Uppenkamp M, Hank JA, Chen BP, Sosman JA, Bridges A, Colamonici OR, Sondel PM (1989) Blood 74: 343-53 Prostaglandin E2 restrains macrophage maturation via E prostanoid receptor 2/protein kinase A signaling. Zaslona Z, Serezani CH, Okunishi K, Aronoff DM, Peters-Golden M (2012) Blood 119: 2358-67 Organization of the gene for human platelet/endothelial cell adhesion molecule-1 shows alternatively spliced isoforms and a functionally complex cytoplasmic domain. Kirschbaum NE, Gumina RJ, Newman PJ (1994) Blood 84: 4028-37 Repetitive weekly cycles of interleukin 2: effect of outpatient treatment with a lower dose of interleukin 2 on non-major histocompatibility complex-restricted killer activity. Goldstein D, Sosman JA, Hank JA, Weil-Hillman G, Moore KH, Borchert A, Bechhofer R, Storer B, Kohler PC, Levitt D (1989) Cancer Res 49: 6832-9 Lymphokine-activated killer activity induced by in vivo interleukin 2 therapy: predominant role for lymphocytes with increased expression of CD2 and leu19 antigens but negative expression of CD16 antigens. Weil-Hillman G, Fisch P, Prieve AF, Sosman JA, Hank JA, Sondel PM (1989) Cancer Res 49: 3680-8 Natural killer cells activated by interleukin 2 treatment in vivo respond to interleukin 2 primarily through the p75 receptor and maintain the p55 (TAC) negative phenotype. Weil-Hillman G, Voss SD, Fisch P, Schell K, Hank JA, Sosman JA, Sugamura K, Sondel PM (1990) Cancer Res 50: 2683-91 Dysregulated human myeloid nuclear differentiation antigen expression in myelodysplastic syndromes: evidence for a role in apoptosis. Briggs RC, Shults KE, Flye LA, McClintock-Treep SA, Jagasia MH, Goodman SA, Boulos FI, Jacobberger JW, Stelzer GT, Head DR (2006) Cancer Res 66: 4645-51 Aberrant accumulation of undifferentiated myeloid cells in the adipose tissue of CCR2-deficient mice delays improvements in insulin sensitivity. Gutierrez DA, Kennedy A, Orr JS, Anderson EK, Webb CD, Gerrald WK, Hasty AH (2011) Diabetes 60: 2820-9 NOD B-cells are insufficient to incite T-cell-mediated anti-islet autoimmunity. Moore DJ, Noorchashm H, Lin TH, Greeley SA, Naji A (2005) Diabetes 54: 2019-25 A phase I trial of continuous infusion interleukin-4 (IL-4) alone and following interleukin-2 (IL-2) in cancer patients. Sosman JA, Fisher SG, Kefer C, Fisher RI, Ellis TM (1994) Ann Oncol 5: 447-52 Pharmacological inhibition and genetic deficiency of plasminogen activator inhibitor-1 attenuates angiotensin II/salt-induced aortic remodeling. Weisberg AD, Albornoz F, Griffin JP, Crandall DL, Elokdah H, Fogo AB, Vaughan DE, Brown NJ (2005) Arterioscler Thromb Vasc Biol 25: 365-71 Platelet endothelial cell adhesion molecule-1 (PECAM-1/CD31): alternatively spliced, functionally distinct isoforms expressed during mammalian cardiovascular development. Baldwin HS, Shen HM, Yan HC, DeLisser HM, Chung A, Mickanin C, Trask T, Kirschbaum NE, Newman PJ, Albelda SM (1994) Development 120: 2539-53 Establishment of an EBV-positive lymphoblastoid cell line that grows as a lymphoma in nude mice and expresses membrane CD2 molecules. Roncella S, Ramarli D, Cooper MK, Forni M, Caretto P, Rowe M, Francia di Celle P, Sessarego M, Foà R, Forni G (1990) Int J Cancer 45: 299-307 CTLA-41g in combination with anti-CD40L prolongs xenograft survival and inhibits anti-gal ab production in GT-Ko mice. Yin D, Ma L, Shen J, Byrne GW, Logan JS, Chong AS (2002) Am J Transplant 2: 41-7 CD98 modulates integrin beta1 function in polarized epithelial cells. Cai S, Bulus N, Fonseca-Siesser PM, Chen D, Hanks SK, Pozzi A, Zent R (2005) J Cell Sci 118: 889-99 Zinc-reversible antimicrobial activity of recombinant calprotectin (migration inhibitory factor-related proteins 8 and 14). Sohnle PG, Hunter MJ, Hahn B, Chazin WJ (2000) J Infect Dis 182: 1272-5 Regulatory defects in Cbl and mitogen-activated protein kinase (extracellular signal-related kinase) pathways cause persistent hyperexpression of CD40 ligand in human lupus T cells. Yi Y, McNerney M, Datta SK (2000) J Immunol 165: 6627-34 Immunoregulation by T cells. I. Characterization of the IEk-specific Lbd self-reactive T cell clone that helps, suppresses and contrasupresses B cell responses. Quintáns J, Suzuki H, Sosman JA, Shah PD (1986) J Immunol 136: 1974-81 Induction of tolerance to heart allografts in high responder rats by combining anti-CD4 with CTLA4Ig. Yin D, Fathman CG (1995) J Immunol 155: 1655-9 IL-15 Superagonist-Mediated Immunotoxicity: Role of NK Cells and IFN-γ. Guo Y, Luan L, Rabacal W, Bohannon JK, Fensterheim BA, Hernandez A, Sherwood ER (2015) J Immunol 195: 2353-64 Promotion of allograft survival by CD4+CD25+ regulatory T cells: evidence for in vivo inhibition of effector cell proliferation. Lee MK, Moore DJ, Jarrett BP, Lian MM, Deng S, Huang X, Markmann JW, Chiaccio M, Barker CF, Caton AJ, Markmann JF (2004) J Immunol 172: 6539-44 Distinct peptide loading pathways for MHC class II molecules associated with alternative Ii chain isoforms. Bikoff EK, Kenty G, Van Kaer L (1998) J Immunol 160: 3101-10 A critical, invariant chain-independent role for H2-M in antigen presentation. Swier K, Brown DR, Bird JJ, Martin WD, Van Kaer L, Reiner SL (1998) J Immunol 160: 540-4 MHC class II expression in double mutant mice lacking invariant chain and DM functions. Kenty G, Martin WD, Van Kaer L, Bikoff EK (1998) J Immunol 160: 606-14 De novo central nervous system processing of myelin antigen is required for the initiation of experimental autoimmune encephalomyelitis. Tompkins SM, Padilla J, Dal Canto MC, Ting JP, Van Kaer L, Miller SD (2002) J Immunol 168: 4173-83 Plasmodium berghei infection in mice induces liver injury by an IL-12- and toll-like receptor/myeloid differentiation factor 88-dependent mechanism. Adachi K, Tsutsui H, Kashiwamura S, Seki E, Nakano H, Takeuchi O, Takeda K, Okumura K, Van Kaer L, Okamura H, Akira S, Nakanishi K (2001) J Immunol 167: 5928-34
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