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Creative Data Solutions (CDS) is a Vanderbilt Shared Resource and has extensive experience in providing effective and robust solutions to challenges pertaining to research data using modern informatics and bioinformatics approaches.
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Connections to Dextran Sulfate are shown below. Double-click or tap a node for more information.
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- Factor XI activation in a revised model of blood coagulation.
Gailani D, Broze GJ
(1991) Science 253: 909-12 - Mutant p53 prolongs NF-κB activation and promotes chronic inflammation and inflammation-associated colorectal cancer.
Cooks T, Pateras IS, Tarcic O, Solomon H, Schetter AJ, Wilder S, Lozano G, Pikarsky E, Forshew T, Rosenfeld N, Rozenfeld N, Harpaz N, Itzkowitz S, Harris CC, Rotter V, Gorgoulis VG, Oren M
(2013) Cancer Cell 23: 634-46 - Editing of the gut microbiota reduces carcinogenesis in mouse models of colitis-associated colorectal cancer.
Zhu W, Miyata N, Winter MG, Arenales A, Hughes ER, Spiga L, Kim J, Sifuentes-Dominguez L, Starokadomskyy P, Gopal P, Byndloss MX, Santos RL, Burstein E, Winter SE
(2019) J Exp Med 216: 2378-2393 - Hypoxia-inducible factor augments experimental colitis through an MIF-dependent inflammatory signaling cascade.
Shah YM, Ito S, Morimura K, Chen C, Yim SH, Haase VH, Gonzalez FJ
(2008) Gastroenterology 134: 2036-48, 2048.e1-3 - Deletion of Mtgr1 sensitizes the colonic epithelium to dextran sodium sulfate-induced colitis.
Martinez JA, Williams CS, Amann JM, Ellis TC, Moreno-Miralles I, Washington MK, Gregoli P, Hiebert SW
(2006) Gastroenterology 131: 579-88 - Identification and Characterization of Unique Neutralizing Antibodies to Mouse EGF Receptor.
Jae Huh W, Niitsu H, Carney B, McKinley ET, Houghton JL, Coffey RJ
(2020) Gastroenterology 158: 1500-1502 - Raf protects against colitis by promoting mouse colon epithelial cell survival through NF-kappaB.
Edelblum KL, Washington MK, Koyama T, Robine S, Baccarini M, Polk DB
(2008) Gastroenterology 135: 539-51 - Colon-specific delivery of a probiotic-derived soluble protein ameliorates intestinal inflammation in mice through an EGFR-dependent mechanism.
Yan F, Cao H, Cover TL, Washington MK, Shi Y, Liu L, Chaturvedi R, Peek RM, Wilson KT, Polk DB
(2011) J Clin Invest 121: 2242-53 - Claudin-1 regulates intestinal epithelial homeostasis through the modulation of Notch-signalling.
Pope JL, Bhat AA, Sharma A, Ahmad R, Krishnan M, Washington MK, Beauchamp RD, Singh AB, Dhawan P
(2014) Gut 63: 622-34 - MTG16 contributes to colonic epithelial integrity in experimental colitis.
Williams CS, Bradley AM, Chaturvedi R, Singh K, Piazuelo MB, Chen X, McDonough EM, Schwartz DA, Brown CT, Allaman MM, Coburn LA, Horst SN, Beaulieu DB, Choksi YA, Washington MK, Williams AD, Fisher MA, Zinkel SS, Peek RM, Wilson KT, Hiebert SW
(2013) Gut 62: 1446-55 - BVES regulates c-Myc stability via PP2A and suppresses colitis-induced tumourigenesis.
Parang B, Kaz AM, Barrett CW, Short SP, Ning W, Keating CE, Mittal MK, Naik RD, Washington MK, Revetta FL, Smith JJ, Chen X, Wilson KT, Brand T, Bader DM, Tansey WP, Chen R, Brentnall TA, Grady WM, Williams CS
(2017) Gut 66: 852-862 - Peroxisome proliferator-activated receptor δ promotes colonic inflammation and tumor growth.
Wang D, Fu L, Ning W, Guo L, Sun X, Dey SK, Chaturvedi R, Wilson KT, DuBois RN
(2014) Proc Natl Acad Sci U S A 111: 7084-9 - Ornithine Decarboxylase in Macrophages Exacerbates Colitis and Promotes Colitis-Associated Colon Carcinogenesis by Impairing M1 Immune Responses.
Singh K, Coburn LA, Asim M, Barry DP, Allaman MM, Shi C, Washington MK, Luis PB, Schneider C, Delgado AG, Piazuelo MB, Cleveland JL, Gobert AP, Wilson KT
(2018) Cancer Res 78: 4303-4315 - MTGR1 is required for tumorigenesis in the murine AOM/DSS colitis-associated carcinoma model.
Barrett CW, Fingleton B, Williams A, Ning W, Fischer MA, Washington MK, Chaturvedi R, Wilson KT, Hiebert SW, Williams CS
(2011) Cancer Res 71: 1302-12 - EGFR-mediated macrophage activation promotes colitis-associated tumorigenesis.
Hardbower DM, Coburn LA, Asim M, Singh K, Sierra JC, Barry DP, Gobert AP, Piazuelo MB, Washington MK, Wilson KT
(2017) Oncogene 36: 3807-3819 - BVES is required for maintenance of colonic epithelial integrity in experimental colitis by modifying intestinal permeability.
Choksi YA, Reddy VK, Singh K, Barrett CW, Short SP, Parang B, Keating CE, Thompson JJ, Verriere TG, Brown RE, Piazuelo MB, Bader DM, Washington MK, Mittal MK, Brand T, Gobert AP, Coburn LA, Wilson KT, Williams CS
(2018) Mucosal Immunol 11: 1363-1374 - Neonatal colonization of mice with LGG promotes intestinal development and decreases susceptibility to colitis in adulthood.
Yan F, Liu L, Cao H, Moore DJ, Washington MK, Wang B, Peek RM, Acra SA, Polk DB
(2017) Mucosal Immunol 10: 117-127 - DSS-induced damage to basement membranes is repaired by matrix replacement and crosslinking.
Howard AM, LaFever KS, Fenix AM, Scurrah CR, Lau KS, Burnette DT, Bhave G, Ferrell N, Page-McCaw A
(2019) J Cell Sci 132: - Increased Epithelial Oxygenation Links Colitis to an Expansion of Tumorigenic Bacteria.
Cevallos SA, Lee JY, Tiffany CR, Byndloss AJ, Johnston L, Byndloss MX, Bäumler AJ
(2019) mBio 10: - Activation of the epidermal growth factor receptor in macrophages regulates cytokine production and experimental colitis.
Lu N, Wang L, Cao H, Liu L, Van Kaer L, Washington MK, Rosen MJ, Dubé PE, Wilson KT, Ren X, Hao X, Polk DB, Yan F
(2014) J Immunol 192: 1013-23 - Calprotectin protects against experimental colonic inflammation in mice.
Aranda CJ, Ocón B, Arredondo-Amador M, Suárez MD, Zarzuelo A, Chazin WJ, Martínez-Augustin O, Sánchez de Medina F
(2018) Br J Pharmacol 175: 3797-3812 - The apolipoprotein E-mimetic peptide COG112 inhibits NF-kappaB signaling, proinflammatory cytokine expression, and disease activity in murine models of colitis.
Singh K, Chaturvedi R, Barry DP, Coburn LA, Asim M, Lewis ND, Piazuelo MB, Washington MK, Vitek MP, Wilson KT
(2011) J Biol Chem 286: 3839-50 - Lack of MMP10 exacerbates experimental colitis and promotes development of inflammation-associated colonic dysplasia.
Koller FL, Dozier EA, Nam KT, Swee M, Birkland TP, Parks WC, Fingleton B
(2012) Lab Invest 92: 1749-59 - ErbB2 and ErbB3 regulate recovery from dextran sulfate sodium-induced colitis by promoting mouse colon epithelial cell survival.
Zhang Y, Dubé PE, Washington MK, Yan F, Polk DB
(2012) Lab Invest 92: 437-50 - Four jointed box 1 promotes angiogenesis and is associated with poor patient survival in colorectal carcinoma.
Al-Greene NT, Means AL, Lu P, Jiang A, Schmidt CR, Chakravarthy AB, Merchant NB, Washington MK, Zhang B, Shyr Y, Deane NG, Beauchamp RD
(2013) PLoS One 8: e69660 - L-arginine supplementation improves responses to injury and inflammation in dextran sulfate sodium colitis.
Coburn LA, Gong X, Singh K, Asim M, Scull BP, Allaman MM, Williams CS, Rosen MJ, Washington MK, Barry DP, Piazuelo MB, Casero RA, Chaturvedi R, Zhao Z, Wilson KT
(2012) PLoS One 7: e33546 - Dietary selenium deficiency exacerbates DSS-induced epithelial injury and AOM/DSS-induced tumorigenesis.
Barrett CW, Singh K, Motley AK, Lintel MK, Matafonova E, Bradley AM, Ning W, Poindexter SV, Parang B, Reddy VK, Chaturvedi R, Fingleton BM, Washington MK, Wilson KT, Davies SS, Hill KE, Burk RF, Williams CS
(2013) PLoS One 8: e67845 - Bilirubin prevents acute DSS-induced colitis by inhibiting leukocyte infiltration and suppressing upregulation of inducible nitric oxide synthase.
Zucker SD, Vogel ME, Kindel TL, Smith DL, Idelman G, Avissar U, Kakarlapudi G, Masnovi ME
(2015) Am J Physiol Gastrointest Liver Physiol 309: G841-54 - Berberine promotes recovery of colitis and inhibits inflammatory responses in colonic macrophages and epithelial cells in DSS-treated mice.
Yan F, Wang L, Shi Y, Cao H, Liu L, Washington MK, Chaturvedi R, Israel DA, Cao H, Wang B, Peek RM, Wilson KT, Polk DB
(2012) Am J Physiol Gastrointest Liver Physiol 302: G504-14 - Deletion of cationic amino acid transporter 2 exacerbates dextran sulfate sodium colitis and leads to an IL-17-predominant T cell response.
Singh K, Coburn LA, Barry DP, Asim M, Scull BP, Allaman MM, Lewis ND, Washington MK, Rosen MJ, Williams CS, Chaturvedi R, Wilson KT
(2013) Am J Physiol Gastrointest Liver Physiol 305: G225-40 - Inactivation of the p19(ARF) tumor suppressor affects intestinal epithelial cell proliferation and integrity.
Farmer TE, Williams CS, Washington MK, Hiebert SW
(2008) J Cell Biochem 104: 2228-40 - The human intestinal microbiota of constipated-predominant irritable bowel syndrome patients exhibits anti-inflammatory properties.
Gobert AP, Sagrestani G, Delmas E, Wilson KT, Verriere TG, Dapoigny M, Del'homme C, Bernalier-Donadille A
(2016) Sci Rep 6: 39399 - Murine colitis is mediated by vimentin.
Mor-Vaknin N, Legendre M, Yu Y, Serezani CH, Garg SK, Jatzek A, Swanson MD, Gonzalez-Hernandez MJ, Teitz-Tennenbaum S, Punturieri A, Engleberg NC, Banerjee R, Peters-Golden M, Kao JY, Markovitz DM
(2013) Sci Rep 3: 1045 - Protective roles of alpha-calcitonin and beta-calcitonin gene-related peptide in spontaneous and experimentally induced colitis.
Thompson BJ, Washington MK, Kurre U, Singh M, Rula EY, Emeson RB
(2008) Dig Dis Sci 53: 229-41
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