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Creative Data Solutions (CDS) is a Vanderbilt Shared Resource and has extensive experience in providing effective and robust solutions to challenges pertaining to research data using modern informatics and bioinformatics approaches.
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Connections to Naphthalenes are shown below. Double-click or tap a node for more information.
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- Substrate-selective COX-2 inhibition decreases anxiety via endocannabinoid activation.
Hermanson DJ, Hartley ND, Gamble-George J, Brown N, Shonesy BC, Kingsley PJ, Colbran RJ, Reese J, Marnett LJ, Patel S
(2013) Nat Neurosci 16: 1291-8 - Parabronchial smooth muscle constitutes an airway epithelial stem cell niche in the mouse lung after injury.
Volckaert T, Dill E, Campbell A, Tiozzo C, Majka S, Bellusci S, De Langhe SP
(2011) J Clin Invest 121: 4409-19 - p120(ctn) acts as an inhibitory regulator of cadherin function in colon carcinoma cells.
Aono S, Nakagawa S, Reynolds AB, Takeichi M
(1999) J Cell Biol 145: 551-62 - Aberrant FGFR signaling mediates resistance to CDK4/6 inhibitors in ER+ breast cancer.
Formisano L, Lu Y, Servetto A, Hanker AB, Jansen VM, Bauer JA, Sudhan DR, Guerrero-Zotano AL, Croessmann S, Guo Y, Ericsson PG, Lee KM, Nixon MJ, Schwarz LJ, Sanders ME, Dugger TC, Cruz MR, Behdad A, Cristofanilli M, Bardia A, O'Shaughnessy J, Nagy RJ, Lanman RB, Solovieff N, He W, Miller M, Su F, Shyr Y, Mayer IA, Balko JM, Arteaga CL
(2019) Nat Commun 10: 1373 - Evidence for a role of endothelin 1 and protein kinase C in nitroglycerin tolerance.
Münzel T, Giaid A, Kurz S, Stewart DJ, Harrison DG
(1995) Proc Natl Acad Sci U S A 92: 5244-8 - Structure of a DNA glycosylase that unhooks interstrand cross-links.
Mullins EA, Warren GM, Bradley NP, Eichman BF
(2017) Proc Natl Acad Sci U S A 114: 4400-4405 - Inhibition of drug-resistant mutants of ABL, KIT, and EGF receptor kinases.
Carter TA, Wodicka LM, Shah NP, Velasco AM, Fabian MA, Treiber DK, Milanov ZV, Atteridge CE, Biggs WH, Edeen PT, Floyd M, Ford JM, Grotzfeld RM, Herrgard S, Insko DE, Mehta SA, Patel HK, Pao W, Sawyers CL, Varmus H, Zarrinkar PP, Lockhart DJ
(2005) Proc Natl Acad Sci U S A 102: 11011-6 - Extracellular matrix rigidity promotes invadopodia activity.
Alexander NR, Branch KM, Parekh A, Clark ES, Iwueke IC, Guelcher SA, Weaver AM
(2008) Curr Biol 18: 1295-1299 - Repeated homotypic stress elevates 2-arachidonoylglycerol levels and enhances short-term endocannabinoid signaling at inhibitory synapses in basolateral amygdala.
Patel S, Kingsley PJ, Mackie K, Marnett LJ, Winder DG
(2009) Neuropsychopharmacology 34: 2699-709 - Design, synthesis, and biological evaluation of halogenated N-(2-(4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-8-yl)ethyl)benzamides: discovery of an isoform-selective small molecule phospholipase D2 inhibitor.
Lavieri RR, Scott SA, Selvy PE, Kim K, Jadhav S, Morrison RD, Daniels JS, Brown HA, Lindsley CW
(2010) J Med Chem 53: 6706-19 - NMR-based modification of matrix metalloproteinase inhibitors with improved bioavailability.
Hajduk PJ, Shuker SB, Nettesheim DG, Craig R, Augeri DJ, Betebenner D, Albert DH, Guo Y, Meadows RP, Xu L, Michaelides M, Davidsen SK, Fesik SW
(2002) J Med Chem 45: 5628-39 - Conformational requirements for norepinephrine uptake inhibition by phenethylamines in brain synaptosomes. Effects of alpha-alkyl substitution.
de Jong AP, Fesik SW, Makriyannis A
(1982) J Med Chem 25: 1438-41 - Discovery of (R)-2-(6-Methoxynaphthalen-2-yl)butanoic Acid as a Potent and Selective Aldo-keto Reductase 1C3 Inhibitor.
Adeniji A, Uddin MJ, Zang T, Tamae D, Wangtrakuldee P, Marnett LJ, Penning TM
(2016) J Med Chem 59: 7431-44 - Kinetic processivity of the two-step oxidations of progesterone and pregnenolone to androgens by human cytochrome P450 17A1.
Gonzalez E, Guengerich FP
(2017) J Biol Chem 292: 13168-13185 - Targeting prostaglandin E2 receptors as an alternative strategy to block cyclooxygenase-2-dependent extracellular matrix-induced matrix metalloproteinase-9 expression by macrophages.
Pavlovic S, Du B, Sakamoto K, Khan KM, Natarajan C, Breyer RM, Dannenberg AJ, Falcone DJ
(2006) J Biol Chem 281: 3321-8 - Absolute configuration of tert-butyl-1-(2-methylnaphthyl)phosphine oxide.
Wang F, Wang Y, Polavarapu PL, Li T, Drabowicz J, Pietrusiewicz KM, Zygo K
(2002) J Org Chem 67: 6539-41 - Cannabinoid receptor 1 suppresses transient receptor potential vanilloid 1-induced inflammatory responses to corneal injury.
Yang Y, Yang H, Wang Z, Varadaraj K, Kumari SS, Mergler S, Okada Y, Saika S, Kingsley PJ, Marnett LJ, Reinach PS
(2013) Cell Signal 25: 501-11 - Structure-Function Studies of Naphthalene, Phenanthrene, Biphenyl, and Their Derivatives in Interaction with and Oxidation by Cytochromes P450 2A13 and 2A6.
Shimada T, Takenaka S, Kakimoto K, Murayama N, Lim YR, Kim D, Foroozesh MK, Yamazaki H, Guengerich FP, Komori M
(2016) Chem Res Toxicol 29: 1029-40 - Reverse type I binding spectra of human cytochrome P450 1B1 induced by flavonoid, stilbene, pyrene, naphthalene, phenanthrene, and biphenyl derivatives that inhibit catalytic activity: a structure-function relationship study.
Shimada T, Tanaka K, Takenaka S, Foroozesh MK, Murayama N, Yamazaki H, Guengerich FP, Komori M
(2009) Chem Res Toxicol 22: 1325-33 - Phospholipases stimulate secretion in RBL mast cells.
Cohen JS, Brown HA
(2001) Biochemistry 40: 6589-97 - Modification of cytochrome P450 1A2 enzymes by the mechanism-based inactivator 2-ethynylnaphthalene and the photoaffinity label 4-azidobiphenyl.
Yun CH, Hammons GJ, Jones G, Martin MV, Hopkins NE, Alworth WL, Guengerich FP
(1992) Biochemistry 31: 10556-63 - Studies on modified hemoglobins. 1. Preparation and properties of a hemoglobin containing heme only in -chains.
Waterman MR, Gondko R, Yonetani T
(1971) Arch Biochem Biophys 145: 448-55 - Homology model of RSK2 N-terminal kinase domain, structure-based identification of novel RSK2 inhibitors, and preliminary common pharmacophore.
Nguyen TL, Gussio R, Smith JA, Lannigan DA, Hecht SM, Scudiero DA, Shoemaker RH, Zaharevitz DW
(2006) Bioorg Med Chem 14: 6097-105 - The importance of large-amplitude motions for the interpretation of mid-infrared vibrational absorption and circular dichroism spectra: 6,6'-dibromo-[1,1'-binaphthalene]-2,2'-diol in dimethyl sulfoxide.
Heshmat M, Baerends EJ, Polavarapu PL, Nicu VP
(2014) J Phys Chem A 118: 4766-77 - Measurement of plasma S-adenosylmethionine and S-adenosylhomocysteine as their fluorescent isoindoles.
Capdevila A, Wagner C
(1998) Anal Biochem 264: 180-4 - A pilot study of active vitamin D administration and insulin resistance in African American patients undergoing chronic hemodialysis.
Hung AM, Sundell MB, Plotnikova NE, Bian A, Shintani A, Ellis CD, Siew ED, Ikizler TA
(2013) J Ren Nutr 23: 185-93 - Absolute configuration of an axially chiral sulfonate determined from its optical rotatory dispersion, electronic circular dichroism, and vibrational circular dichroism spectra.
Covington CL, Raghavan V, Smuts JP, Armstrong DW, Polavarapu PL
(2017) Chirality 29: 670-676
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